Antibody Fragment Used in Genetic Engineering Techniques

 

Prof. David Givol spent a significant part of his career investigating the structure-function relationship of antibodies. He identified the smallest fragment of antibody containing all its binding properties, i.e. the part of the molecule responsible for recognizing the foreign substance attacking the organism.

 

 

Today, this fragment – called Fv – is used in genetic engineering techniques for producing synthetic antibodies for treating various diseases.