Blending Art and Science

English
Dr. Barton Rubenstein with his wife, Shereen, and their children, Ari (1), Sabrina (5) and Ben (8). “Oasis”
 
 

 

For many, art and science seem to be worlds apart: One, a world open to abstract interpretation and meaning; the other, a world that strives for certainties that are real and quantifiable. But are these worlds really so separate?
 
Dr. Barton Rubenstein’s unique and diverse life experiences have allowed him to get these two realms to collide: He draws upon his scientific background to create mesmerizing works of art.
 
Trained in physics and mechanical engineering at Haverford College, Pennsylvania, Rubenstein then spent the next six years at the Weizmann Institute of Science, completing his M.Sc. in mathematics and computer science in 1990 and his Ph.D. in neurobiology in 1994.
 
Under the guidance of Prof. Dov Sagi, Rubenstein focused his research on the visual sciences – how we recognize objects and perceive patterns, motion and depth. One avenue he researched in particular was texture discrimination. “There was so much confusion in this field at the time. For example, it usually takes 1 to 10 seconds to find, say, a squirrel sitting in a tree. On the other hand, discriminating between the textures of bark of two different trees takes only a fraction of a second. This is unusual; the pathways used by the brain to process such information are complicated, so no one understood how it could be carried out so quickly. Those were exciting times for me, as we were the first ones to create a model to explain this phenomenon, resulting in its publication in the Journal of the Optical Society of America.”
 
For Rubenstein, the Weizmann Institute was his pathway to success. “The research was simply intoxicating. The phenomenal friendship I forged with my supervisor, Dov, motivated me so much, we would sometimes spend six hours a day just philosophizing about ideas for experiments and how to solve problems. I even remember, on a couple of occasions, Dov would persuade me to take time off from lab work so that I could really delve into researching a particular topic, and only when I had a firm grasp of it was I ‘allowed’ to return. I cannot think of any other institute that would encourage such an approach.
 
“Upon completing my Ph.D., there was already a position waiting for me at the National Institutes of Health. However, when I saw that campus, I was taken aback. Compared to the beautiful and nurturing atmosphere of the Weizmann Institute, I felt disorientated at NIH – all the departments were segregated and there was no connectivity or cross-talk between them like those I had experienced at Weizmann. It was at this moment that I began to doubt my future as a scientist.”
 
Rubenstein spent the next two years thinking about art. Realizing that he wanted to make “the world a little better and more beautiful for the next generation,” he took a great leap and decided to leave science and choose art as his life’s work. Developing a keen interest in sculpture, he created seven or eight works during the first year and had his first show in 1996.
 
At Rubenstein Studios in Chevy Chase, Maryland, Rubenstein calls into play his physics and engineering background to incorporate visual phenomena and interesting perceptual illusions into sculptures of bronze, steel, stone and glass. He creates these sculptures for public spaces and commercial and corporate venues, as well as for private residences.
 
One such sculpture is “Oasis” – three arching and twisting forms rising out of a bed of stones – which Rubenstein donated to the Weizmann Institute. As water glides down its surfaces and falls off its edges, it creates undulating translucent sheets of water, the steel body glistening in the sunshine. “Something inside of me felt the need to come full circle – the institute had given me so much knowledge and inspiration, and I wanted to give something of myself back to it through my artwork.”    
 

To view Rubenstein’s artwork, visit his website at www.rubensteinstudios.com

 
Dr. Barton Rubenstein with his wife, Shereen, and their children, Ari (1), Sabrina (5) and Ben (8). “Oasis”
English

Crystal Clear

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Prof. Osnat Herzberg. sabbaticals at the Weizmann Institute
 
 

 

Antibiotics have transformed our ability to treat many infectious diseases that were killers only a few decades ago. But with increasing use, many bacteria are becoming resistant to the most commonly prescribed antibiotic treatments – so much so, that resistance to antibiotics has become one of the world’s most pressing health problems. There is therefore a need to develop new and potent antibiotics with novel modes of action. To design such drugs, however, it is very important to solve the 3-D crystal structures of the bacterial target proteins, since they are the templates with which the drug interacts, just as a key fits into a lock.
 
This has been, for many years, the aim of Weizmann Institute graduate Prof. Osnat Herzberg, who continues her endeavor at the Center for Advanced Research in Biotechnology (CARB) of the University of Maryland, USA.
 
For her Ph.D. research, Herzberg chose to specialize in protein X-ray crystallography. “Although structural biology was a relatively young subject, many great scientific breakthroughs were being made, and I just had to be in the forefront of this field,” says Herzberg.
 
Herzberg received her master’s degree in geo-isotope research from the Weizmann Institute in 1976 and then, under the guidance of Prof. Ada Yonath and Prof. John Moult (a visiting scientist at the time), went on to pursue her Ph.D. studies in what was then the Institute’s Structural Chemistry Department, receiving her degree in 1982. Her research focused on understanding the structural basis for the action of beta-lactamases – enzymes produced by some bacteria that give them resistance to certain antibiotics such as penicillin. During her postdoctoral studies, carried out at the University of Alberta, Edmonton, Canada, she eventually managed to solve the structure of the enzyme in 1987.
 
Among a number of research topics that she pursues at CARB, where she has now been for almost 20 years, Herzberg maintains her interest in determining the structure of beta-lactamases as a means of understanding their function and mechanism of action. But something about the Weizmann Institute keeps drawing her back. Herzberg jumped at the opportunity to work in the Weizmann Institute’s Israel Structural Proteomics Center, headed by Prof. Joel Sussman, which is equipped with state-of-the-art instumentation for protein production, crystallization and 3-D structure determination, and develops high throughput approaches for determining the 3-D structures of human protein targets of medical importance. For two three-month periods in 2004 and 2005, she took sabbatical leaves, supported by the Weizmann Institute’s Weston Visiting Professorship and the Helen and Milton A. Kimmelman Center, respectively, in which she immersed herself in “hands-on” bench work.
 
“I felt the best way to really understand and appreciate the work carried out by my students was to place myself in their shoes, and I am now able to provide better guidance and to adopt innovative techniques that I myself learned at the Weizmann Institute.”   
 
The Israel Structural Proteomics Center is funded by the Ministry of Science and Technology; the EU Structural Proteomics in Europe (SPINE) project; and the Divadol Foundation for Technology Development.
 
Prof. Osnat Herzberg
Chemistry
English

A Web of Protection

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Guy Levy-Yurista. Internet security expert
 
 
 
"There is always a certain charm to exploring nature, trying to understand how the world works," says Dr. Guy Levy-Yurista. He was fortunate enough to grow up close to the Weizmann Institute of Science, where the many youth activities that the Institute had to offer were within easy reach, nurturing his fascination with physics and mathematics, and helping him to discover the fun of science.
 
This early stimulating environment helped sow the seeds of academic success. Guy was accepted to a unique army undergraduate program, Talpiot – one of the most rigorous undergraduate programs in the world – at the Hebrew University of Jerusalem, and he later pursued a master's degree at Tel Aviv University.
 
For Guy, the next step was obvious: to study for a Ph.D. Because wine tasting has always been a prominent hobby of Guy's – he was editor of the Israeli Wine and Gourmet magazine from 1998 to 2002, and is now President of the Wharton EMBA 32 East Wine Club – he thought about doing a Ph.D. in France. "I even took several French language courses in preparation!"
 
But Guy's adviser at Tel Aviv University pointed him in the direction of Prof. Asher Friesem of the Weizmann Institute of Science's Physics of Complex Systems Department. "The research that I would be conducting at the Weizmann Institute sounded much more interesting and fun, and the wine scene in Israel was becoming more and more exciting, so I decided to accept."
 
Guy's research at the Institute focused on advanced optical communication elements for potential use in optical communication networks. "I even kept the lab temperature low so that I could keep my wine collection under my optical bench! It was the safest place I had, as I was still renting at the time." Guy went on to graduate in 2001 with a Ph.D. in applied physics.
 
As a result of his research, Yeda Ltd. – the commercial arm of the Institute – helped establish a start-up company, GWS Photonics, in the U.S., their products having been under development at the Weizmann Institute for the previous ten years.
 
"The Institute really played a shaping role throughout my life, both as a child and as an adult. Thanks to the Weizmann Institute, I have gained a breadth and depth of thinking that enables me to dive into details as well as seeing the big picture.
 
"The Weizmann Institute is all about getting research done for the greater good of science. All the scientists were so dedicated, both to their research and to each other, supporting each other and putting aside their own work to help others first. I really admired that."
 
Guy currently lives in the U.S. and has been working at America Online (AOL) as a principal product manager for the past three years. He has led product teams in reshaping AOL's Internet safety and security strategy, becoming an expert in the fields of spyware, viruses, phishing and I.D. theft, supporting a near $100-million total in marketing campaigns. He has managed full product cycles, from inception to definition, development, testing, launch, maintenance and discontinuation, that support over 15 million users.
 
Guy is also in the midst of doing a fourth degree – an MBA from the Program for Executives at the highly acclaimed Wharton School of Business of the University of Pennsylvania.
 
"Science," says Guy, "is most exciting and gratifying, but it doesn't have to stop at academia. A background in science can really help carry business into new realms."

 

 
Dr. Guy Levy-Yurista
English

Breaking the Silence

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Profs. Karen Avraham and Yoram Groner. Uncovering genes

 

Working toward breaking a silence to which millions of children and adults are condemned, Karen Avraham, Associate Professor of the Sackler Faculty of Medicine at Tel Aviv University and Chair of the Department of Human Molecular Genetics and Biochemistry, has been studying the Israeli and Palestinian deaf populations to identify the genes and mutations that lead to hearing impairment.

 
While studying for her undergraduate degree at the University of Washington, St. Louis, Karen decided to accept the mundane job of washing glassware for a molecular biology lab. "As time went by, I found myself washing less glassware and immersing myself more in the research that was being carried out in the lab: the cloning of tubulin genes; tubulin proteins make up microtubules that serve as structural components within cells," explains Karen.
 
After completing her first degree in biology in 1984, Karen decided to immigrate to Israel. "I decided I wanted to study something more medically related, and I found the perfect combination in Prof. Yoram Groner's lab in the Weizmann Institute's Molecular Genetics Department; he offered me the opportunity to work with him in unraveling the genetic basis of Down's syndrome."
 
Groner had discovered a certain gene a few years earlier and found that when it is overexpressed, it leads to some of the symptoms of Down's syndrome. To study the gene further, Karen created a transgenic mouse model – one of the first to be made not only at the Weizmann Institute, but in the whole of Israel at the time – allowing them to look at the expression of the gene and understand its effects more thoroughly.
 
"The atmosphere in Yoram's lab was fantastic. It was such a supportive environment; there was no such thing as 'it can't be done'," says Karen. "I was also fortunate to be surrounded by so many role models at the Institute, particularly the women, who served as an inspiration to women like myself."
 
"There is no doubt in my mind that the Institute was instrumental in my receiving an excellent postdoctoral position at the National Cancer Institute of the National Institutes of Health, Maryland, where I began working on the genetics of deafness."
 
Karen returned to Israel after completing her postdoctoral training and accepted the faculty position at Tel Aviv University, where she currently works, allowing her to continue researching the genetics of deafness. She has also been collaborating with a Palestinian professor, Moien Kanaan of Bethlehem University, with whom Groner had acquainted her, and together they have published several papers in leading journals.
 
Profs. Karen Avraham and Yoram Groner.
English

Networks of Success

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Dr. Shulamit Levenberg, leader in tissue engineering

 

 

Appearing on Scientific American’s list of 50 leading scientists, businessmen and policymakers for the year 2006 places Dr. Shulamit Levenberg in position as a world leader in tissue engineering.
 
According to Levenberg, now a senior lecturer in the Biomedical Engineering Department at the Technion – Israel Institute of Technology in Haifa, it was her days as a graduate student at the Weizmann Institute’s Feinberg Graduate School that shaped her future as a scientist.
 
“People come to Weizmann out of a love of science,” she says. “There is a special research atmosphere at the Institute, in the midst of its beautiful lawns and trees.” Levenberg recalls the Feinberg “rotation” system – a unique approach enabling master’s students to become exposed to various research fields and methods before choosing a topic. “This approach was one of the reasons I chose Feinberg: It enables you to begin your graduate work by experiencing numerous fields and techniques, allowing you to keep all your options open before making a final decision.” 
 
Levenberg’s third rotation stop, in Prof. Benjamin Geiger’s lab in the Molecular Cell Biology Department, led directly to her Ph.D. program: Her doctoral work focused on communication between cells. Relying on Geiger’s collaborations with experts in materials science, microscopy and computing, she learned to incorporate information from diverse fields of research. “Prof. Geiger’s ability to bring people from different fields together to solve a scientific question gave me inspiration,” she says. “Beyond the technical methods, Weizmann scientists and students gave me essential tools: how to plan an experiment, how to solve problems, how to think.”
 
She also remembers with nostalgia the social gatherings of the research group, the encounters in the hallways and the walks in the orchards adjoining the Institute. This was a particularly intensive period: In parallel to her scientific work, she married and started a family. But her personal life was by no means an obstacle: Trusting his students’ motivation, Geiger grants them a great deal of independence, allowing them to place family concerns high on their list of priorities.
 
Upon completing her Ph.D., Levenberg pursued postdoctoral studies in the tissue engineering lab of Prof. Robert Langer at the Massachusetts Institute of Technology. Her research, which earned her recognition in Scientific American, is an important milestone in the effort to create artificial tissues that promise one day to replace damaged human organs. Together with the lab’s multidisciplinary team of engineers, computer scientists, chemists and biologists, Levenberg generated muscle tissue using a network of blood vessels. The tissue was successfully implanted in mice and even promoted growth of the new blood vessels essential for feeding the transplanted cells, thus overcoming one of the greatest obstacles to tissue transplantation.
 
After her postdoctoral studies, Levenberg returned to Israel and joined the Technion, receiving the faculty position of senior lecturer and becoming head of a laboratory in the Biomedical Engineering Department, where she continues her work in tissue engineering.
 
In facing the daily challenge of managing a lab, she goes back to the guidance she received from her two mentors, Geiger and Langer, when supervising her own students: “Whenever I run into questions, I try to think how they would have acted and try to draw lessons from their knowledge and experience.”
Dr. Shulamit Levenberg
English

The Straw That Broke the Bacterium’s Back

English
Dr. Moshe Frommer. Most amazing invention
 
 
 
With a view overlooking the lush green campus of the Weizmann Institute of Science, Dr. Moshe Frommer, general manager of the Rehovot-based company, Purofilter®, sits on his home balcony in Rehovot and reminisces. It was here that he first arrived, 45 years ago, as a young doctoral student studying under the guidance of Prof. Israel Millo in the Institute's Polymer Department. Since then, much water has flown down many rivers, including the Yarkon River, which is host to a collection of germs and pollutants. But Frommer’s work over those years has resulted in an invention that allows one to drink from it without any fear for one’s health.  
 
Time magazine chose this invention as “one of the most amazing inventions of 2005”; it received an INDEX International Design and Innovation Award for “the design most likely to improve life for many people”; and the February 2006 issue of Forbes magazine has selected it as one of the “10 things that will change the way we live.”
The invention is a reusable plastic straw containing a long-lasting filter filled with bacteria-killing resins. In the time it takes to suck the polluted water up the 30 cm length of the LifeStraw®, the water gets purified, reaching the drinker’s mouth completely germ free. 
 
Frommer: “Around one-sixth of the world’s population suffers from a shortage of clean drinking water. Every day, thousands die from waterborne diseases. My dream has been to help find a solution for those millions of people that are faced with this problem. Today, that dream is close to becoming a reality. About two million already use the water purification straws, and I hope that in the near future, the tens of millions of people in countries that don’t have access to clean drinking water will be able to benefit from them.” A single straw, which can be hung around the neck for personal use, costs only three dollars and can filter 700 liters – the amount of water a single person drinks in a year. Tests show that the filter kills a large variety of bacteria and viruses, and the straw does not clog from cloudy or turbid water. Last, but certainly not least, the purified water also tastes good.
 
Dr. Frommer received his B.Sc. and M.Sc. in chemistry from the Technion, and his Ph.D. from the Feinberg Graduate School at the Weizmann Institute of Science. He remembers his years of research, in what was then the Polymer Department, as among the best of his life, and he still meets from time to time with his Ph.D. adviser, Prof. Millo, and other friends he made at that time. After graduating, he went on to work at Hydranautics, a company based in the industrial park next to the Weizmann Institute, which made membranes for desalinization. In the following years, he continued to work on developing various methods of water purification.
 
LifeStraw® was born about three years ago when a Danish company came up with the idea and was looking for someone who could help fulfill its requirements. They approached Frommer who, through his expertise, was able not only to supply the suitable germ-killing material for the straws, but also to design the structure and composition of the LifeStraw® itself. The bactericidal resin is presently produced in Israel; the plastic straws in China. Today, the straws are distributed by humanitarian aid organizations. Time correspondents, for instance, first learned of them in Pakistan, where they were given to earthquake victims. 
 
Frommer runs the whole enterprise by computer from his home near the Institute. “The sight of the Institute is a constant reminder of values I absorbed while studying there,” he muses. “Curiosity, sticking to goals, the will to help people better their situations – I feel lucky that I’ve been able to turn these values into deeds.”
 
LifeStraw® in action
 
 

The Right to Water

 
The burden of waterborne diseases that plague the developing world is immense. According to statistics provided by the World Health Organization:*
• 1.8 million people die of a diarrheal disease (including cholera) every year, 90% of them children under 5
• 88% of these deaths are attributed to unsafe water supplies, inadequate sanitation and lack of hygiene
• Improved water supply reduces diarrhea morbidity by between 6% and 25%
 
*From the WHO website: http://www.who.int/water_sanitation_health/publications/facts2004/en/   (accessed August 8, 2006)
 
 
Dr. Moshe Frommer
Environment
English

The Science of Seizures

English
Prof. Tallie Z. Baram. Seized with a love of science
 
 

 

One day, on rounds with a chief physician, Prof. Tallie Z. Baram - then a medical resident - was told to inject a hormone, ACTH, into an infant suffering from a particular form of infant epilepsy. "Why do I give this to a baby with epilepsy?" she asked. The answer was: "Because it works." To Baram, a graduate of the Weizmann Institute’s Feinberg Graduate School who now heads the epilepsy research program at the University of California at Irvine, the unanswered question became a challenge: "I think this is one of the moments that inspired me to find out what happens in the brains of children when they have a seizure."
 
Baram had always wanted to be involved in science. Born in Tel Aviv, she spent two years in Ethiopia as a child, an experience that, she says, opened her eyes to the diversity of the world. While in high school, her love of science brought her to a Weizmann Institute summer science camp. After receiving a B.Sc. in biology from Tel Aviv University, she came to the Institute to study neuroscience under the guidance of Prof. Yitzhak Koch, now of the Neurobiology Department. At Weizmann, her work focused on a neuropeptide hormone released by the brain. Baram fondly remembers meeting interesting people in the biology library at midnight or holding freewheeling coffee-fueled discussions in the neurobiology lab of Prof. Menahem Segal at 2:00 a.m. It was, she says, "an awesome teaching environment, where independent thinking was encouraged."
 
Baram’s Ph.D. work earned her a John F. Kennedy Prize from the Feinberg Graduate School. She used the prize to attend a two-year course of medical studies designed for Ph.D.s at the University of Miami School of Medicine. Baram was one of 35 accepted into the program, out of around 1,000 applicants. She then did a residency in pediatrics, combined with a fellowship in child neurology, at the Baylor College of Medicine in Houston, Texas.
 
After holding faculty positions at the University of Texas and the University of Southern California, Baram moved to the University of California at Irvine in 1995. There she founded the UCI Epilepsy Research Center, where she is currently executive director. Epilepsy affects 50 million people worldwide; it is not one single disease but around 40 related syndromes. Baram has gained international recognition for her studies of how high fever in children affects brain neurons, causing febrile seizures. She showed that prolonged seizures can eventually result in changes to the developing brain and in some cases lead to epilepsy later in life. These studies might make it possible to predict susceptibility to certain forms of epilepsy; they also shed light on the development of healthy brains.
 
While investigating the neurological basis of the type of infant epilepsy known as infantile spasms, Baram revealed the mechanism by which certain hormones, including ACTH, produce their effect. Her research in this area may form the basis of new, more effective drugs for treating the condition. In December 2005, Baram became the first woman to receive the Epilepsy Research Recognition Award of the American Epilepsy Society, considered the top honor in the world for epilepsy research.
 
Prof. Tallie Baram
English

Crystal Memories

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Dr. David and Sandy Haas. research in wartime

 

 

In 1967, David Haas, a young postdoctoral researcher at the Institute, wrote a paper on a new process he'd developed for freezing biological crystals. Time passed; he changed careers and forgot about it. More than 30 years later, over a friendly lunch with a professor, Haas was reminded about his crystallization work and learned that his achievement at the Institute had revolutionized research. Says Haas: “That conversation was a real journey 'back to the future.’” 
 
Haas and his wife, Sandy, arrived at Haifa Port in December 1966, and they still vividly recall the contrasts: “We'd come from the formal atmosphere of Great Britain’s Royal Institute, where the Friday evening lecture series was a black-tie affair,” says Sandy. “In Israel, T-shirts and sandals were almost never out of place, and our apartment at Lunenfeld-Kunin overlooked a lovely orange grove.”  The Haases agree that it was the casual, informal nature of the Weizmann Institute as well as the availability and sharing of state-of-the-art equipment that contributed so significantly to the freedom to experiment and be creative in the lab. 
 
Haas began his postdoctoral research in crystallography – the study of crystal structures by X-ray diffraction – under Prof. Wolfie Traub of the Institute's Chemistry Department. He developed a method of freezing, called cryocrystallography, which stabilizes protein crystals otherwise subject to damage or destruction during the complex processes required to analyze them. This method is now standard for biological and protein crystal analyses. In 1967, only two or three protein structures were known; the data collection process required a large number of crystals and took about six to twelve months. As a result of Haas's research, the same analysis can today be completed in two to three hours, and some 20,000 protein structures are now known.
 
The development of cryocrystallography was completed within just six months, in the time leading up to, during and shortly after the Six-Day War. Most scientists and staff were called to military service or evacuated, and Haas remained behind with only a handful of researchers. His most vivid memories are unrelated to science: “As a volunteer in the Institute's fire brigade, I camped out on the steps of the Stone Administration Building and saw the artillery flashes over Jerusalem. I listened to the mid-war radio broadcast of former Weizmann Institute president and Israeli Foreign Minister Abba Eban's address to the U.N.”
 
Haas’s research was cut short by the instability of life after the Six-Day War, and he left Israel to continue briefly at Purdue University. Soon after, he chose a career in security systems, and he and his wife successfully founded several companies. Today, with some 50 patents to their credit, Haas is president of TECCO Corporation operating out of Suffern, New York. Among his inventions is a self-expiring identification badge made of  “paper that tells time.”
 
The Haases never lost their ties with Israel: All three of their sons participated in youth programs in Israel, and Stuart, the oldest, made aliyah in 1989. “So many things have changed since our first trip in 1967,” remarks Sandy, “but I was struck even then by how far Israel had come in such a short time.”  Recently, the Haases have taken their involvement in the country one step further and reestablished their connection with the Institute in the process: Since 2002, they have served as Diplomats of the American Committee for the Weizmann Institute of Science.
Dr. David and Sandy Haas
English

Science in the service of the police

English

 

Dr. Elazar Tzadok. Scientific crime fighting
 

 

Dr. Elazar Tzadok, Director of the Identification and Forensic Science Division of the Israel Police, first donned his police uniform at the age of 49, with the rank of brigadier general. This occured in October 1999, one year before the outbreak of the recent wave of violence. "Normally, our role is to support a variety of investigations, from apartment break-ins and stolen cars to murder, rape, or armed robbery," says Tzadok. "Due to the current security situation, the division also performs important national functions, such as identifying explosives used by terrorists, helping the security forces to find out where explosives are being prepared, and assisting in the identification of victims of terrorist acts.

If a car bomb has been used, our task is to check where the car came from, whether its plates were forged or stolen, and so on. In the event of a shooting, we have a ballistics lab that analyzes the empty shells found on the scene to determine the kinds of weapons used and establish a connection between different acts."To provide a scientific basis for identifying crime suspects, the division employs cutting-edge technology as well as traditional methods. The division is also responsible for polygraph testing, analyzing handwriting in the case of forged passports and ID cards, and identifying and characterizing counterfeit money.

All seized illicit drugs pass through the division's analytical lab.Tzadok received a B.Sc. and M.Sc. in Chemistry from Tel Aviv University and did his army service in the technological unit of the IDF's Intelligence Corps. That was where he met his future Ph.D. adviser, Prof. Yehuda Mazur, who served as consultant to the unit. Tzadok followed Mazur to the Weizmann Institute of Science."I started my doctorate at the Institute in 1979 and spent four years in the Organic Chemistry Department.

Those were among the best years of my life. I felt that I was in the right place doing the right thing. The high scientific level, the international atmosphere, and the serene environment allowed me to delve into my favorite subjects." After completing his Ph.D., Tzadok received an offer from the technological unit of the IDF's Intelligence Corps to create a new analytical chemistry division. He later held other senior positions in the Intelligence Corps, twice went abroad for postdoctoral studies, and worked in the private sector before joining the Israel Police.
 
Tzadok is married to Nechama, who earned an M.Sc. from the Weizmann Institute's Science Teaching Department. They have three sons: Avi, who is completing a second degree in physics; Adir, who is studying for a degree in Communications and Political Science; and Nir, who is in high school.
 
 
Dr. Elazar Tzadok
English

Gold at Sydney

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Stephanie Cook. Gold medalist and doctor

 

 

 

 

 

 

 

 

 

 

 

Great Britain's Stephanie Cook snatched a dramatic gold at the Sydney Olympics - pistol shooting, fencing, swimming, riding, and finally running her way to victory in the first ever Olympic women's pentathlon.

But she's not only an all-round athlete. The 28-year-old started training full-time only a year earlier and then won Olympic selection at the World Cup Competition in Mexico. To do so, she had to put her career, as a physician, on hold.

 

It was at Oxford that Cook picked up her passion for the pentathlon - a contest demanding the utmost in both endurance and technical versatility. Treading a most unusual how-to-survive-medical-school path, her days were spent mastering the nuts and bolts of medicine while picking up the ancient art of fencing, learning how to shoot at a target with a 0.177 air pistol, and somehow squeezing in cross-country running, swimming, and horseback riding, a childhood favorite. "I've always tried to cram a lot into life," says Cook. Her manner is down-to-earth and her enthusiasm is catching. "I may have taken what started as a hobby to an extreme, but at the end of the day, I still enjoy the sport." Raised in Ayr, Scotland, one of the experiences Cook "crammed" in - at the age of 18 - was a summer here in Rehovot, at Weizmann's Bessie Lawrence International Summer Science Institute. She credits this experience with broadening her horizons in terms of the great variety of medical research. It also enhanced a previous interest in surgery, sparked during high school, when she met Professor Sir Roy Calne, a leading liver-transplant surgeon. (Calne, of Addenbrooke Hospital, Cambridge, paved the way to successful kidney, heart, and liver transplants following his discovery that a new drug, azathioprine, could stop graft rejection.) While at the Weizmann Institute, Cook took part in bone marrow transplantation research conducted by Prof. Yair Reisner's team in the Immunology Department.

 

But it wasn't all lab-work and no play. In what she describes as a fantastic summer, Cook also remembers climbing desert wadis, learning outdoor survival skills, and cooling off in the Golan waterfalls, adding that she's still in contact with some of her fellow Weizmann students.

 

How does Stephanie Cook, the doctor, meet up with Stephanie Cook, the world-class athlete? "Obviously, when you're training at this level you really push your body to the extreme, says Cook. "And in fact it's an interesting experience understanding the anatomy and physiology and therefore what the body is actually going through."

 

Round-robin fencing

One field that Cook claims was invaluable to her success is sports psychology. "It's incredibly important to believe in one's ability, and to be able to turn around a negative situation to something positive," she stresses. This belief, combined with running - her forte and her greatest love - is what won the day at Sydney. Cook started the 3,000-meter run in 8th place, assigned according to her accumulated points from the first four events. Undeterred, she tore off in pursuit of the leaders, Britain's Kate Allenby and America's Emily deRiel. The crowd's roar swelled as she narrowed the gap with each passing second, until she flew past deRiel 300 meters from the finish line, claiming gold.

 

 

What comes next? Despite the exciting career opportunities awaiting her as an athlete, Cook will soon lay down her sword and sneakers - in exchange for a scalpel. "It took me a while to decide what I truly wanted rather than what opportunities were out there. 

Riding

But I love medicine and I feel that I've taken my sport as far as it can go." After the World Championships next summer, Cook plans to return to a surgical rotation doing accident and emergency work and will perhaps specialize in sports medicine in the future.
 

Meanwhile, those of us here at the Weizmann Institute might be intrigued by the thought that our sports facilities served as a training ground for a future Olympic gold medallist.

 
 
 
 
 
Stephanie Cook
English

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