Anti-Inflammatory Compounds

 

For nearly two decades, Prof. David Wallach has studied receptors for the tumor necrosis factor, or TNF, an immune system substance that controls the damaging processes associated with inflammation. In these studies, Wallach identified two classes of proteins that block TNF activity.

 

 

The proteins identified by Wallach are being used in clinical trials as anti-inflammatory compounds that may control rheumatoid arthritis and inflammatory bowel diseases (Crohn's disease and colitis).