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Leukemia

Leukemic cells
27.07.2017

Analyzing cancer stem cell populations in first-time patients enabled researchers to predict who was most likely to suffer a relapse

Bone marrow EPCR+ hematopoietic (blood-forming) stem cell in an anticoagulant niche
03.11.2015

How does the body keep replenishing the supply of blood cells all our lives? Two pathways must work together

NPM1 interacts with DNA polymerase eta and regulates polymerase eta-promoted TLS. Assay of polymerase eta and NPM1 in unirradiated (l) and ultraviolet irradiated cells ((c) after one hour, (r) after 18 hours). Blue: DNA in the nucleus; green: polymerase eta–NPM1 interaction
29.12.2014

A mechanism for keeping DNA repair mistakes to a minimum might advance the development of cancer drugs

 

Pre-leukemic stem cells (top) with both mutated and healthy copies of the RUNX1 gene already display some of the characteristics of acute myeloid leukemia (AML). When the non-mutated copy of the gene is inactivated, disruptions in the spindle-assembly-checkpoint phase of cell division trigger cell death
29.09.2013

Weizmann Institute researchers discover that a “standoff” between a mutated gene and its normal counterpart keeps certain cancer cells alive...

Bone Marrow Transplant
18.07.2010
Using laboratory animals, Prof. Yair Reisner developed the concept of “megadose” bone marrow transplants. The approach, developed...
Catching a Sneak
13.04.2005

Weizmann Institute Scientists reveal the shape of a protein that helps retroviruses break into cells

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Prof. Yair Reisner
12.12.2002
Prof. Yair Reisner of the Institute's Immunology Department will be awarded the Daniele Chianelli Prize on December 15, 2002...
Life-Saving Discrepancy: Study Shows Effectiveness of Mismatched Bone Marrow Transplants
22.10.1998
REHOVOT, Israel  October 22, 1998  For many leukemia sufferers, bone marrow transplantation is their only hope....

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