DNA repair

DNA

DNA "Repair Enzymes" Tricked into Producing Mutations

01.10.1994

Enzymes that repair DNA damage may end up preserving mutations in certain situations, according to new research

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A portion of the mouse hypothalamus reveals that the protein made by the Otp gene (green) is expressed in all the neurons (red) that drive hunger – and the combined color is therefore yellow. It was known that in the developing brain, Otp is needed for the generation of these neurons. The study found that during adulthood, Otp is crucial for causing these neurons to express AgRP, a major hunger-promoting substance

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