Biochemistry

MRI brain scans of mice with Gaucher disease Type III. The scan of a mouse that received the new treatment (left) shows a significant reduction in tissue inflammation (blue) compared to an untreated mouse (right)

Improving the Recipe for Gene Therapy

13.10.2024

Bioinformatics and Computational Biology, Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

An innovative treatment for Gaucher disease has produced promising results in mice, giving hope to patients after decades of research

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New Circuit Made of DNA Has Everything Wired In

03.09.2024

Nanoscience, Organic Chemistry, Biochemistry, Technology & Applications, Biotechnology

Weizmann Institute of Science researchers were thrilled when they managed to observe the birth of a protein made by a single DNA molecule: No one had...

Peyote in bloom (Photo: Guy Yosef Keren)

Cactus Dreams: Revealing the Secrets of Mescaline Making

15.08.2024

Biochemistry, Brain & Behavior, Plants and Agriculture

Scientists tackle the thorny issue of securing a sustainable source of the psychedelic for drug development

Phagophore

Mouths Wide Shut: How Cellular Cleaning Out Is Kept in Check

03.06.2024

Structural Biology, Biochemistry, Molecular and Cell Biology, Evolution and Development

Autophagic organelles found to actively restrict the size of their mouths

AI Flexes Its Muscles

AI Flexes Its Muscles

11.04.2024

Bioinformatics and Computational Biology, Biochemistry, Molecular and Cell Biology

A machine learning model sheds new light on muscle development

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Proteins without Parents

14.02.2024

Organic Chemistry, Biochemistry, Evolution and Development

Using three AI protein prediction tools, a Chinese-Israeli study uncovers new wrinkles in the folding story of “orphan” proteins

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The Human Touch: Designing “Humanized” Antibodies That Work

25.01.2024

Bioinformatics and Computational Biology, Biochemistry, Disease, Drugs & Diagnostics

A new algorithm may greatly speed up the process of engineering therapeutic antibodies

Scanning electron microscope images of the enamel layer enveloping mouse teeth

Newly Discovered Autoimmune Disorder Disrupts Tooth Enamel Development

02.12.2023

Biochemistry, Nutrition, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

Celiac disease in children might be associated with sensitivity to a protein abundant in dairy products. The new findings may facilitate the disorder...

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Moonshot Provides Blueprint for Future Pandemic Drugs

10.11.2023

Structural Biology, Biochemistry, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics

An open-access format for drug discovery is helping design medications against potential viral threats

An illustration showing four modular enzyme fragments (highlighted) that Weizmann Institute’s CADENZ method can combine to generate active enzymes at a hitherto unseen rate

Building Better Enzymes – by Breaking Them Down

12.01.2023

Bioinformatics and Computational Biology, Biochemistry, Evolution and Development, Environment, Energy, Plants and Agriculture, Climate, Benefiting Humanity, Biotechnology

In a major step toward greener industry, Weizmann Institute scientists create a computational method for generating enzymes with unprecedented...

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A tumor sample from a human patient with the most common type of lung cancer (adenocarcinoma). Senescent cells are highlighted by their expression of the p16 (red) and the PD-L1 (green) proteins. Cell nuclei are in blue

Unclogging the Immune System

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