Genetics

Magnetic resonance imaging (MRI) scans of the brain in three children with a missing copy of the Chaserr gene. The scans performed at age 8 months or 4 years (top row) reveal structural changes in the brain, including reduced volume of the brain stem (asterisks) and decreased myelin coating of nerves (arrows) in deep-seated brain areas. These changes are less apparent at 1 month of age (bottom row)

Emma’s Gene

24.07.2025

Biochemistry, Brain & Behavior, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Scientists discover a rare disorder caused by a missing genetic brake

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Sensing Fat

29.05.2025

Nutrition, Molecular and Cell Biology, Genetics

Weizmann Institute researchers reveal that the nervous system can sense fat tissue and that blocking this ability protects mice from metabolic...

Fat cells

Slimming with Mitch

05.05.2025

Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Blocking Mitch, an energy-control protein, prevents fat accumulation in human cells

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Wake-Up Call for Dormant Cancer

22.04.2025

Cancer, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute researchers reveal how breast cancer cells enter a state of dormancy, remaining undetected for years, and why they suddenly wake...

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The Master Switch Turning Immune Cells into Cancer Eradicators

10.04.2025

Cancer, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Genetics

Researchers in Prof. Ido Amit’s lab identify a gene that reprograms macrophages into cancer-promoting cells — and show how to switch it off

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When Proteins Go on Strike

27.02.2025

Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Evolution and Development, Genetics

Weizmann Institute researchers forced thousands of yeast proteins to go on a surprise strike – and uncovered their previously unknown roles in some...

The Short and the Long of Protein Tails

The Short and the Long of Protein Tails

06.02.2025

Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Evolution and Development, Genetics

Without their tails, thousands of proteins would be unable to fulfill their vital roles. Changes to these tails can cause rare genetic diseases

A tumor sample from a human patient with the most common type of lung cancer (adenocarcinoma). Senescent cells are highlighted by their expression of the p16 (red) and the PD-L1 (green) proteins. Cell nuclei are in blue

Unclogging the Immune System

21.10.2024

Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute researchers reveal how aging cells evade our immune systems – and propose developing an innovative treatment for age-related...

MRI brain scans of mice with Gaucher disease Type III. The scan of a mouse that received the new treatment (left) shows a significant reduction in tissue inflammation (blue) compared to an untreated mouse (right)

Improving the Recipe for Gene Therapy

13.10.2024

Bioinformatics and Computational Biology, Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

An innovative treatment for Gaucher disease has produced promising results in mice, giving hope to patients after decades of research

An image of tissue from the human small intestine obtained with the help of fluorescent dyes that made it possible to mark numerous proteins in parallel, thereby mapping out the various proteins produced in each part of the intestinal villi

Navigating the Digestive Tract

07.08.2024

Nutrition, Molecular and Cell Biology, Genetics

A comprehensive gene expression atlas of the human small intestine uncovers the secrets of nutrient absorption and defense against infection

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Magnetic resonance imaging (MRI) scans of the brain in three children with a missing copy of the Chaserr gene. The scans performed at age 8 months or 4 years (top row) reveal structural changes in the brain, including reduced volume of the brain stem (asterisks) and decreased myelin coating of nerves (arrows) in deep-seated brain areas. These changes are less apparent at 1 month of age (bottom row)

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