Genetics

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

06.09.2023

Stem Cells, Molecular and Cell Biology, Evolution and Development, Fertility, Genetics

The complete, day 14 synthetic models may open new avenues of research into infertility, drug testing and growth of tissues for transplant – as well...

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Surviving on an Empty Battery

17.08.2023

Viruses & Microorganisms, Molecular and Cell Biology, Immunology, Evolution and Development, Genetics

A newly discovered immune strategy protects bacteria and more advanced species, from corals to bees

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Gaining Weight? You Have a Bone to Pick with Calcium

31.07.2023

Brain & Behavior, Nutrition, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute scientists discovered a gene that may cause weight gain in older people, regardless of their diet

Lung macrophages infected with the human cytomegalovirus. Cells harboring an active infection are in bright green

Prepared for War: How Cells Survive Viral Invasion

28.06.2023

Viruses & Microorganisms, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Genetics

High levels of defensive proteins offer protection against a hostile takeover by herpes viruses

Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered

Thugs in the Cellular Neighborhood

08.02.2023

Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to recruitment of...

Bacteriophages attacking a bacterium. Source: Prof. Graham Beards

Viruses Gain the Upper Hand

25.10.2022

Viruses & Microorganisms, Molecular and Cell Biology, Evolution and Development, Genetics

Weizmann Institute scientists reveal how viruses outwit cellular immune systems

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Desperate Cancer Cells

31.08.2022

Cancer, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

How tumors mutate their way out of a crisis – and become drug resistant in the process

Development of synthetic mouse embryo models inside beakers

Without Egg, Sperm or Womb: Synthetic Mouse Embryo Models Created Solely from Stem Cells

01.08.2022

Stem Cells, Molecular and Cell Biology, Evolution and Development, Genetics, Technology & Applications

The method opens new vistas for studying how stem cells self-organize into organs and may in the future help produce transplantable tissues

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“Zip Codes” Tell RNA Where to Go

26.07.2022

Molecular and Cell Biology, Evolution and Development, Genetics

Weizmann Institute scientists solve the riddle of how RNA molecules get to their designated locations

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Creating the Cells That Can Be Everything and More

12.07.2022

Stem Cells, Molecular and Cell Biology, Immunology, Evolution and Development, Genetics

Removing a newly discovered “lock” from DNA’s packaging can restore limitless abilities to early cells

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