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Bioinformatics and Computational Biology
An illustration showing four modular enzyme fragments (highlighted) that Weizmann Institute’s CADENZ method can combine to generate active enzymes at a hitherto unseen rate

Building Better Enzymes – by Breaking Them Down

12.01.2023
Bioinformatics and Computational Biology, Biochemistry, Evolution and Development, Environment, Energy, Plants and Agriculture, Climate, Benefiting Humanity, Biotechnology
In a major step toward greener industry, Weizmann Institute scientists create a computational method for generating enzymes with unprecedented...
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Sweetness That Comes at a Price: Sugar Substitutes May Affect the Human Body in Unanticipated Ways

18.08.2022
Bioinformatics and Computational Biology, Personalized Medicine, Nutrition, Viruses & Microorganisms, Disease, Drugs & Diagnostics
A controlled trial suggests that non-nutritive sweeteners affect the human gut microbes and may alter glucose metabolism
(l-r) Prof. Amos Tanay, Dr. Yoav Mayshar, Dr. Markus Mittnenzweig and Dr. Yonatan Stelzer. Orchestrated ensembles

Life’s Moving Picture

29.07.2021
Bioinformatics and Computational Biology, Stem Cells, Systems Biology, Molecular and Cell Biology, Evolution and Development, Genetics
Reconstructing the intricate process of embryonic development one cellular frame at a time
Dr. Efi Efrati and Dr. Luiz Da Silva

Solving a Plant Cell "Parking Garage" Puzzle

26.05.2021
Bioinformatics and Computational Biology, Theoretical Physics, Materials Science, Structural Biology, Biochemistry
Biological organelles may be messy and crowded, but sometimes only an exact mathematical description will do 
MBZUAI President, Professor Eric Xing and President of the Weizmann Institute, Professor Alon Chen in Abu Dhabi

A Senior Delegation from the Weizmann Institute of Science Visits MBZUAI Campus in Abu Dhabi

03.05.2021
Math & Computer Science, Computer Vision, Bioinformatics and Computational Biology, Astrophysics, Personalized Medicine, Genetics, Technology & Applications, Benefiting Humanity, Biotechnology
The two parties discussed their new collaboration initiative to advance the field of artificial intelligence research
Slow Synchronization Keeps Heart Cells Beating in Time

Slow Synchronization Keeps Heart Cells Beating in Time

22.04.2021
Bioinformatics and Computational Biology, Theoretical Physics
For a beating heart cell, noise is a problem. Researchers showed that single cells can regulate their inner noise
When the Beads Line Up

When the Beads Line Up

05.04.2021
Bioinformatics and Computational Biology, Systems Biology, Evolution and Development, Genetics
Conserved elements reveal vital spots in the noncoding, regulatory, portions of the genome 
melanoma cells

Bacteria May Aid Anti-Cancer Immune Response

17.03.2021
Bioinformatics and Computational Biology, Cancer, Personalized Medicine, Systems Biology, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics
The findings of a new study may explain the microbiome-immunotherapy connection
Evolved to Stop Bacteria, Designed for Stability

Evolved to Stop Bacteria, Designed for Stability

15.03.2021
Bioinformatics and Computational Biology, Structural Biology, Viruses & Microorganisms, Disease, Drugs & Diagnostics
New proteins, created through long-distance collaboration, might lead to the reversal of antibiotic resistance in certain bacteria 
How

How "Great" Was the Great Oxygenation Event?

25.02.2021
Bioinformatics and Computational Biology, Biochemistry, Evolution and Development
A look at enzyme evolution suggests life figured out how to use oxygen long before the main event 

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Dumpster Diving in Cancer Tissue Uncovers an Immune Evasion Mechanism

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

Peripheral sensory neurons in a laboratory dish

Unlocking a Secret Nerve Cell Regenerator

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Surviving on an Empty Battery

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A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta
06.09.2023
Human Embryo Models Grown from Stem Cells
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17.08.2023
Surviving on an Empty Battery
14.08.2023
A “Jupiter” Hotter than the Sun