Bioinformatics and Computational Biology

Without the c-Kit gene, colon cancer cells grow in a disorderly, aggregated manner and are invasive (A); when c-Kit expression is restored in these cells, they revert to a more normal organization (B)

The Double Life of a Cancer Gene

15.09.2013

Space & Physics, Cancer, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A cancer-causing gene can prevent the deadly spread of a tumor at a later point in malignancy

“Deregulation scores” of hundreds of brain tumor patients: Each row corresponds to a pathway (that is, a biochemical process), and each column to a sample taken from a patient. Every colored spot stands for a number – the value of the “deregulation score” of the corresponding pathway, as determined for a particular patient. Dark blue stands for the activity of the pathway in normal brain tissue, whereas dark red indicates a high level of deviation from normal behavior. The clearly distinct group of normal b

The Path to Personalized Prognosis

13.05.2013

Cancer, Personalized Medicine, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A new approach to personalized cancer therapy profiles a tumor by its biological pathways

Dr. Frida Belinky

Noncoding Sequences Get Equal Listing

07.05.2013

Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A greatly expanded database will give scientists around the world a powerful new tool for life sciences research

Yeast cell atlas: image by Michal Breker

An Atlas for Cells

08.04.2013

Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A new map of protein routes in the cell holds some surprises for researchers

Dr. Jasmin Fisher

Making Sense of a Complex Situation

24.02.2013

Bioinformatics and Computational Biology

Dr. Jasmin Fisher’s computer models reveal how cells make decisions

(l-r) Dr. Tuval Ben Yehezkel, Prof. Ehud Shapiro and Tamir Biezuner

A Proofreader for DNA

14.02.2013

Biochemistry, Bioinformatics and Computational Biology

Programmable devices made of biological molecules can identify exact DNA sequences in living cells

Prof. Vered Rom-Kedar

A Fragile Equilibrium

16.12.2012

Viruses & Microorganisms, Immunology, Disease, Drugs & Diagnostics, Bioinformatics and Computational Biology, Diagnostic Techniques and Drugs

A mathematical model may lead to safer chemotherapy

Drs. Yotam Drier (left) and Gad Getz at the Broad Institute

Cancer at a Breaking Point

16.12.2012

Bioinformatics and Computational Biology

A unique collaboration is helping map out the genetics of cancer

cell and numbers. Image: Thinkstock

Weizmann Institute’s Mathematical Model May Lead to Safer Chemotherapy

12.09.2012

Cancer, Viruses & Microorganisms, Immunology, Disease, Drugs & Diagnostics, Bioinformatics and Computational Biology

The study explains why certain patients develop severe infections after chemotherapy and points to ways of averting this side-effect

Leukemia cells. Image: Wikimedia commons, NIH

Why Chemotherapy Fails

29.05.2012

Biochemistry, Cancer, Bioinformatics and Computational Biology

Research led by Weizmann Institute scientists shows why leukemia often returns

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Top Stories

Multiple Proteins Viewed as Never Before

Getting Cancer to Unmask Itself

They’d Rather Die: The Lesson That Male Roundworms Refuse to Learn

Dr. Omer Kneller (left) and Chen Mor direct a laser beam before it enters the experimental setup. The experiment required a powerful laser beam that could produce exceptionally short, attosecond light pulses. Photo: Noa Yaffe

Matter at the Crossroads

Press Releases

Getting Cancer to Unmask Itself

New Immune Mechanism Revealed in the Cellular Trash

A Broken Heart: Two Types of Scars, Two Paths to Healing