Bioinformatics and Computational Biology

SuperPaths: A map of human biological pathways. Each node represents a biological pathway and every line shows a connection between pathways. Every connected set is a SuperPath containing several related pathways.

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27.05.2015

Genetics, Bioinformatics and Computational Biology

SuperPaths provide a global online resource of genetic interactions

We share many of our genes with sea urchins, but none of the sequences for long non-coding RNAs that regulate those genes

Looking for Links

25.05.2015

Systems Biology, Molecular and Cell Biology, Evolution and Development, Genetics, Bioinformatics and Computational Biology

Non-coding DNA sequences on an evolutionary “fast track” may hold clues to human disease

receptors day and night

Tumors Might Grow Faster at Night

06.10.2014

Cancer, Molecular and Cell Biology, Bioinformatics and Computational Biology

Weizmann Institute scientists reveal that a hormone that keeps us alert also suppresses the spread of cancer

(l-r) Dr. Zohar Mukamel, Zohar Shipony and Prof. Amos Tanay

Cellular Senior Moments

21.07.2014

Cancer, Stem Cells, Molecular and Cell Biology, Immunology, Genetics, Bioinformatics and Computational Biology

As the body’s cell divide and age, mistakes can pile up in the genome's "tags"

Without the c-Kit gene, colon cancer cells grow in a disorderly, aggregated manner and are invasive (A); when c-Kit expression is restored in these cells, they revert to a more normal organization (B)

The Double Life of a Cancer Gene

15.09.2013

Space & Physics, Cancer, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A cancer-causing gene can prevent the deadly spread of a tumor at a later point in malignancy

“Deregulation scores” of hundreds of brain tumor patients: Each row corresponds to a pathway (that is, a biochemical process), and each column to a sample taken from a patient. Every colored spot stands for a number – the value of the “deregulation score” of the corresponding pathway, as determined for a particular patient. Dark blue stands for the activity of the pathway in normal brain tissue, whereas dark red indicates a high level of deviation from normal behavior. The clearly distinct group of normal b

The Path to Personalized Prognosis

13.05.2013

Cancer, Personalized Medicine, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A new approach to personalized cancer therapy profiles a tumor by its biological pathways

Dr. Frida Belinky

Noncoding Sequences Get Equal Listing

07.05.2013

Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A greatly expanded database will give scientists around the world a powerful new tool for life sciences research

Yeast cell atlas: image by Michal Breker

An Atlas for Cells

08.04.2013

Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A new map of protein routes in the cell holds some surprises for researchers

Dr. Jasmin Fisher

Making Sense of a Complex Situation

24.02.2013

Bioinformatics and Computational Biology

Dr. Jasmin Fisher’s computer models reveal how cells make decisions

(l-r) Dr. Tuval Ben Yehezkel, Prof. Ehud Shapiro and Tamir Biezuner

A Proofreader for DNA

14.02.2013

Biochemistry, Bioinformatics and Computational Biology

Programmable devices made of biological molecules can identify exact DNA sequences in living cells

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Top: Overexpression of genes from the B2-SINE family in retinal ganglion neurons led to accelerated growth after injury. Bottom: Ganglion cells after injury without B2-SINE overexpression

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