https://wis-wander.weizmann.ac.il/chemistry/human-touch-designing-“humanized”-antibodies-work
January 25, 2024
In the late nineteenth century, physicians started treating human disease with blood serum extracted from immunized horses. But those extracts – which contained antibodies that target disease agents – often produced disastrous immunological responses. In the late twentieth centur...
https://wis-wander.weizmann.ac.il/life-sciences/there’s-new-hypothesis-your-hypophysis
February 2, 2024
An unexpected observation has led researchers at the Weizmann Institute of Science to challenge a 200-year-old doctrine regarding the embryonic origins of the pituitary gland. Situated at the base of the brain, this pea-sized organ, also known as the hypophysis, plays a centra...
https://wis-wander.weizmann.ac.il/life-sciences/down-rabbit-hole
February 8, 2024
No one would ever confuse a human being with, say, a mouse or a chicken. But at the very start of their different developmental paths, they share a striking similarity. In fact, even the most experienced researchers have a hard time saying whether an embryo in its gastrulation st...
https://wis-wander.weizmann.ac.il/chemistry/proteins-without-parents
February 14, 2024
When Profs. Joel Sussman and Israel Silman were asked to mentor Chinese students online during the COVID-19 pandemic, the last thing they expected to come out of the experience was highly innovative research on protein evolution that could change our understanding of the way new...
https://wis-wander.weizmann.ac.il/life-sciences/toward-treatment-huntington’s-disease
February 26, 2024
The human brain is a well-guarded control center. Its system of blood vessels is surrounded by a densely packed cellular barrier that prevents most substances from getting in or out. This fortified architecture protects the brain, but it can also stop it from getting help when it...
https://wis-wander.weizmann.ac.il/space-physics/how-does-bacterium-know-it’s-time
March 8, 2024
Bacterial cells do not wake up one morning and decide to become parents. But there is a point in their cell cycle – after growing sufficiently and replicating their genomes – when they split in two, creating new cells that then repeat the process. What tells the bacterium that it...
https://wis-wander.weizmann.ac.il/life-sciences/fungus-vs-fungus-newly-identified-yeast-might-prevent-life-threatening-fungal
March 18, 2024
Researchers at the Weizmann Institute of Science have identified a yeast that might be used to prevent invasive candidiasis, a major cause of death in hospitalized and immunocompromised patients. The study, published today in the Journal of Experimental Medicine (JEM), shows that...
https://wis-wander.weizmann.ac.il/space-physics/hundred-million-suns-most-complete-portrait-supernova
March 27, 2024
Humankind has long turned to the skies in search of answers. Accounts of supernovae – exploding stars – go back thousands of years, but while we know today that these events create the building blocks of life itself, the conditions that cause a star to explode still remain very m...
https://wis-wander.weizmann.ac.il/life-sciences/social-hierarchy-even-mice-it’s-complicated
April 3, 2024
For animals, including humans, one’s place in the social hierarchy can affect everything, including one’s health and lifespan. Researchers at the Weizmann Institute of Science have now used a naturalistic approach to studying how mice form social hierarchies, and they discovered...
https://wis-wander.weizmann.ac.il/life-sciences/ai-flexes-its-muscles
April 11, 2024
Life sciences have never been more digital. To learn more about life processes, biologists are collecting massive quantities of data that computer scientists analyze by means of sophisticated computational models that they develop. Over the past few years, Dr. Ori Avinoam of the...