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Israel Silman

Deciphering Gaucher's Disease
Deciphering Gaucher's Disease
01.10.2003
Biochemistry, Brain & Behavior, Disease, Drugs & Diagnostics, Genetics, Structural Biology

New finding may lead to more effective – and affordable – treatments

X-Rays Yield Mechanism of Alzheimer’s Drug
X-Rays Yield Mechanism of Alzheimer’s Drug
01.05.2003
Biochemistry, Brain & Behavior, Disease, Drugs & Diagnostics, Structural Biology

A study of an Alzheimer's drug's activity reveals why lower doses might be just as effective

X-Rays Yield Mechanism of Alzheimer’s Drug
X-Rays Yield Mechanism of Alzheimer’s Drug
24.02.2003
Biochemistry, Brain & Behavior, Disease, Drugs & Diagnostics, Structural Biology
A team of Weizmann scientists has gained new insight into the effects of a newly approved drug, rivastigmine, in...
Dr. Gitay Kryger, Prof. Israel Silmam, and Prof. Joel Sussman
Breaking the Bonds
01.05.2000
Space & Physics, Biochemistry, Structural Biology, Diagnostic Techniques and Drugs

Scientists attempting to catch an enzyme in action got unique 3-D footage of radiation damage, instead

X-ray radiation from a synchrotron source can rapidly damage, in a very specific way, the structure of a protein, as seen by X-ray crystallography. The four images represent a series of electron density maps collected from the same protein crystal. Protein degradation is indicated by the disappearance of the disulfide bond (yellow bar, surrounded by empty blue cage) linking the carbon chains (white balls). These images represent the first-ever recording of experimentally-induced chemical bond breakage usin
Weizmann Institute Scientists Capture The First-Ever 3D Visualization Of How Molecules Break Apart When Exposed To X-Rays
27.01.2000
Space & Physics, Biochemistry, Molecular and Cell Biology, Structural Biology
 
Their findings may yield future measures for preventing radiation-induced health...
X-Rays May Show The Way To Better Alzheimer's Drugs
X-Rays May Show The Way To Better Alzheimer's Drugs
27.12.1999
Disease, Drugs & Diagnostics
Weizmann Institute scientists have elucidated the means by which a plant substance blocks a key brain enzyme involved in...
From Ancient Wisdom to Modern Drug
From Ancient Wisdom to Modern Drug
01.05.1997
Structural Biology
X-ray crystallography reveals how a moss used in Chinese medicine inhibits an enzyme implicated in Alzheimer's disease...
Study Shows How Ancient Chinese Herb May Act As Alzheimer Drug
Study Shows How Ancient Chinese Herb May Act As Alzheimer Drug
01.01.1997
REHOVOT, Israel -- January 1, 1997 -- A new Weizmann Institute...

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Credit: Coleen Murphy, Princeton University, Princeton, NJ

Grabbing a Model by the Throat

“Eight Shining Examples of Excellence”

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Burning Cancer’s Bridges

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Crystalizing Our Comprehension of Malaria

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11.11.2024
“Eight Shining Examples of Excellence”
27.08.2024
The Weizmann Institute of Science Ranked among the World’s Top Ten Academic Institutions
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26.08.2024
A Discovery to Set Your Heart a-Knocking
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