Jacob (Yaqub) Hanna

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

06.09.2023

Stem Cells, Molecular and Cell Biology, Evolution and Development, Fertility, Genetics

The complete, day 14 synthetic models may open new avenues of research into infertility, drug testing and growth of tissues for transplant – as...

Development of synthetic mouse embryo models inside beakers

Without Egg, Sperm or Womb: Synthetic Mouse Embryo Models Created Solely from Stem Cells

01.08.2022

Stem Cells, Molecular and Cell Biology, Evolution and Development, Genetics, Technology & Applications

The method opens new vistas for studying how stem cells self-organize into organs and may in the future help produce transplantable...

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Creating the Cells That Can Be Everything and More

12.07.2022

Stem Cells, Molecular and Cell Biology, Immunology, Evolution and Development, Genetics

Removing a newly discovered “lock” from DNA’s packaging can restore limitless abilities to early cells

Mouse embryo with integrated human cells that contribute to its development

As Naïve as They Get

30.12.2021

Personalized Medicine, Stem Cells, Molecular and Cell Biology, Evolution and Development, Genetics

Prof. Jacob Hanna’s method for growing mouse embryos outside the womb was shortlisted for Science’s Breakthrough of the Year. Another study from...

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Credit: Coleen Murphy, Princeton University, Princeton, NJ

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“Eight Shining Examples of Excellence”

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