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Weizmann Researchers Find Evidence That Links a Molecular Mechanism to Huntington's Disease

Weizmann Researchers Find Evidence That Links a Molecular Mechanism to Huntington's Disease

22.06.1999
Disease, Drugs & Diagnostics
Weizmann researchers have found evidence that an enzyme called transglutaminase (TGase) may be the "smoking gun" behind the deadly disease Huntington's disease (HD). Their study is reported in the June 22 issue of the Proceedings of the National Academy of Sciences.
Weizmann Institute Scientist Designs The First General-Purpose Mechanical Computing Device To Serve As The Basis For A Biological Computer

Weizmann Institute Scientist Designs The First General-Purpose Mechanical Computing Device To Serve As The Basis For A Biological Computer

15.06.1999
Math & Computer Science
The first general-purpose mechanical computer designed for biomolecular and pharmaceutical applications has been developed by Prof. Ehud Shapiro of the Computer Science and Applied Mathematics Department at the Weizmann Institute of Science.  The mechanical computer will be presented today at the Fifth International Meeting on DNA-Based Computers at the Massachusetts Institute of Technology.  
Mechanism Involved in Causing Colon Cancer Discovered at the Weizmann Institute

Mechanism Involved in Causing Colon Cancer Discovered at the Weizmann Institute

11.05.1999
Disease, Drugs & Diagnostics
REHOVOT, Israel -- May 11, 1999 -- Weizmann Institute researchers have discovered a molecular mechanism that may be involved in causing colon cancer, according to a study reported in the May 11 issue of the Proceedings of the National Academy of Sciences.
Blocking Autoimmunity Naturally

Blocking Autoimmunity Naturally

01.03.1999
Disease, Drugs & Diagnostics
Rheumatoid arthritis, juvenile diabetes and psoriasis are all examples of autoimmunity, a condition in which the body attacks its own tissues. One way to treat such conditions is to use drugs that suppress the immune system across the board, but this is a drastic and potentially dangerous measure. Therefore, researchers are searching for selective autoimmunity drugs, which can bring the immune system under control by targeting specific mechanisms.  
Heat-Shock Vaccine Stops Bacteria Dead

Heat-Shock Vaccine Stops Bacteria Dead

01.03.1999
Disease, Drugs & Diagnostics
Autoimmunity, in which the body attacks its own tissues, has traditionally been viewed as spelling nothing but trouble. But now  Weizmann Institute scientists have shown that it's possible to "enlist" an autoimmune mechanism for a beneficial cause -- fighting outside intruders such as bacteria. This new approach may lead to the development of improved vaccines for preventing various infectious diseases and possibly for treating cancerous tumors.
'Plugs' For Drugs Promise Mightier Medicines

'Plugs' For Drugs Promise Mightier Medicines

01.03.1999
Biochemistry
Whether it's one pill several times a day or a self-administered injection, taking medicine frequently can be a major nuisance. Now Weizmann Institute scientists have developed a new approach that may prolong the action of many drugs, making it possible to administer them at much greater intervals without jeopardizing their effectiveness. Immediately after it's taken, the medication's levels in the blood normally surge -- sometimes up to 100 times more than what is needed.  
Bone Marrow Transplants May Be Improved

Bone Marrow Transplants May Be Improved

05.02.1999
Disease, Drugs & Diagnostics
Bone Marrow Transplants May Be Improved Thanks To Discovery Of A Key Mechanism Underlying Human Stem Cell Migration   REHOVOT, Israel - February 5, 1999 - In bone marrow transplantation, a patient receives a transfusion of stem cells, which migrate to the patient's bone marrow and start producing new, healthy blood. But many transplants fail because, usually, very few stem cells make their way from the blood circulation into the recipient's marrow.
Immunity's Nervous Supervisor

Immunity's Nervous Supervisor

01.12.1998
Disease, Drugs & Diagnostics
Our body systems are like sections in an orchestra, "conducted" by the brain. But how exactly does the brain, which is part of the central nervous system, send its messages directly to the other systems? While nerve cells communicate through neurotransmitters, the immune system's T cells, for instance, do their talking through entirely different molecular messengers, the most important ones being cytokines.
How 'Micro' Can We Go?

How 'Micro' Can We Go?

01.12.1998
Materials Science
Microelectronics may be a growth industry, but the devices it produces are getting smaller every year. Just how "micro" can electronic devices go?
New 'Bacteria Bashers' Wipe Out Infection

New 'Bacteria Bashers' Wipe Out Infection

01.12.1998
Disease, Drugs & Diagnostics
It used to be that antibiotics could be trusted to rid the body of a host of bacterial diseases. Today, however, emerging strains of antibiotic-resistant bacteria are speeding ahead, threatening to make existing drugs obsolete. Now, researchers at the Weizmann Institute of Science have developed an original approach that may lead to a radically new way of treating bacterial infections. Natural detergent-like mechanism may lead to potent antimicrobial drugs

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