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Blocking Autoimmunity Naturally
01.03.1999
Disease, Drugs & Diagnostics
Rheumatoid arthritis, juvenile diabetes and psoriasis are all examples of autoimmunity, a condition in which the body attacks its own tissues. One way to treat such conditions is to use drugs that suppress the immune system across the board, but this is a drastic and potentially dangerous measure. Therefore, researchers are searching for selective autoimmunity drugs, which can bring the immune system under control by targeting specific mechanisms.
Heat-Shock Vaccine Stops Bacteria Dead
01.03.1999
Disease, Drugs & Diagnostics
Autoimmunity, in which the body attacks its own tissues, has traditionally been viewed as spelling nothing but trouble. But now Weizmann Institute scientists have shown that it's possible to "enlist" an autoimmune mechanism for a beneficial cause -- fighting outside intruders such as bacteria. This new approach may lead to the development of improved vaccines for preventing various infectious diseases and possibly for treating cancerous tumors.
'Plugs' For Drugs Promise Mightier Medicines
01.03.1999
Biochemistry
Whether it's one pill several times a day or a self-administered injection, taking medicine frequently can be a major nuisance. Now Weizmann Institute scientists have developed a new approach that may prolong the action of many drugs, making it possible to administer them at much greater intervals without jeopardizing their effectiveness. Immediately after it's taken, the medication's levels in the blood normally surge -- sometimes up to 100 times more than what is needed.
Bone Marrow Transplants May Be Improved
05.02.1999
Disease, Drugs & Diagnostics
Bone Marrow Transplants May Be Improved Thanks To Discovery Of A Key Mechanism Underlying Human Stem Cell Migration REHOVOT, Israel - February 5, 1999 - In bone marrow transplantation, a patient receives a transfusion of stem cells, which migrate to the patient's bone marrow and start producing new, healthy blood. But many transplants fail because, usually, very few stem cells make their way from the blood circulation into the recipient's marrow.
Immunity's Nervous Supervisor
01.12.1998
Disease, Drugs & Diagnostics
Our body systems are like sections in an orchestra, "conducted" by the brain. But how exactly does the brain, which is part of the central nervous system, send its messages directly to the other systems? While nerve cells communicate through neurotransmitters, the immune system's T cells, for instance, do their talking through entirely different molecular messengers, the most important ones being cytokines.
How 'Micro' Can We Go?
01.12.1998
Materials Science
Microelectronics may be a growth industry, but the devices it produces are getting smaller every year. Just how "micro" can electronic devices go?
New 'Bacteria Bashers' Wipe Out Infection
01.12.1998
Disease, Drugs & Diagnostics
It used to be that antibiotics could be trusted to rid the body of a host of bacterial diseases. Today, however, emerging strains of antibiotic-resistant bacteria are speeding ahead, threatening to make existing drugs obsolete. Now, researchers at the Weizmann Institute of Science have developed an original approach that may lead to a radically new way of treating bacterial infections. Natural detergent-like mechanism may lead to potent antimicrobial drugs
Life-Saving Discrepancy: Study Shows Effectiveness of Mismatched Bone Marrow Transplants
22.10.1998
Disease, Drugs & Diagnostics
REHOVOT, Israel October 22, 1998 For many leukemia sufferers, bone marrow transplantation is their only hope. Unfortunately, in about 40 percent of terminal cases, patients fail to find a perfectly matched donor among relatives or in any of the donor registries.
New Class of Molecular Magnets May Advance Microelectronics
24.09.1998
Materials Science
REHOVOT, Israel -- September 24, 1998 -- Weizmann Institute scientists have created a new class of magnetic materials made of clusters of inorganic molecules. These molecular magnets, described in the September 24 issue of Nature, display an unusual combination of properties that open up new research possibilities and may lead to a broad range of future applications in the microelectronics industry.
Secrets of the SOS Repair Service
01.09.1998
Biochemistry
Some repair crews just do their job. Others go beyond the call of duty, leaving you better off than you were before the problem occurred. An emergency repair "service" that fixes DNA, the genetic material of cells, belongs to the second type.
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