You are here

Protein recycling


Cancer alters cellular waste-processing machinery, helping it avoid detection by the immune system


A novel technology for profiling protein turnover and degradation offers new insight into diagnosis and understanding the molecular basis of...

op: Mass spectrometry, along with other methods, reveals that the protein CSNAP is the ninth subunit of the COP9 signalosome (CSN) complex. Bottom: COP9 complex subunits compared with those of the 19S proteasome suggest that CSNAP is the corresponding subunit to the smallest proteasome protein, filling in the puzzle of the “missing piece

The protein had evaded detection for decades; without it, cells may turn cancerous

(l-r) Drs. Yishai Levin, Michal Sharon, Maria Füzesi-Levi and Gili Ben-Nisan

The cell’s recycler is a shape shifter that is versatile, subtle and sophisticated

(l-r) Dr. Gili Ben-Nissan, Prof. Yosef Shaul, Dr. Michal Sharon and Oren Moscovitz

How does the cell keep certain vital proteins from getting recycled?

Illustration: helping hand

When one of the cell’s garbage disposal systems is in trouble, another one lends a hand.

(l-r) Prof. Zvulun Elazar, Tomer Shpilka and Hilla Weidberg. Construction details

The proper assembly of a recycling compartment is critical for the life of a cell.