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Dumpster Diving in Cancer Tissue Uncovers an Immune Evasion Mechanism
20.09.2023
Cancer, Systems Biology, Molecular and Cell Biology, Immunology

Cancer alters cellular waste-processing machinery, helping it avoid detection by the immune system

Human lung cancer cells harboring the L858R mutation in the EGFR gene. Cell nuclei are in blue. The red color marks a protein that is present in the cell cytoplasm when the EGFR is active and driving the uncontrolled cell divisions
A Select Group: Study May Bring Improved Therapy to Preselected Lung Cancer Patients
08.08.2023
Cancer, Personalized Medicine, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

Weizmann Institute researchers identify a biomarker that may one day enable a subgroup of lung cancer patients to benefit from relapse-free...

Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered
Thugs in the Cellular Neighborhood
08.02.2023
Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to...

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Desperate Cancer Cells
31.08.2022
Cancer, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

How tumors mutate their way out of a crisis – and become drug resistant in the process

Cultured colorectal cancer cells. Top: Cells that have become resistant to certain forms of chemotherapy and continue to thrive. Bottom: The same cells, which have had the LIP gene inserted and are then treated with chemotherapy drugs
Opposite Effects
02.07.2015
Cancer, Molecular and Cell Biology

What makes cancer cells survive chemotherapy?

Prof. Ehud Shapiro, Dr. Rivka Adar, Adam Spiro and Noa Chapal-Ilani
Finding the Source of Cancer Recurrence
17.07.2012
Biochemistry, Cancer, Math & Computer Science

Do chemotherapy drugs miss a hidden reservoir of cancer cells?

Leukemia cells. Image: Wikimedia commons, NIH
Why Chemotherapy Fails
29.05.2012
Biochemistry, Cancer, Bioinformatics and Computational Biology

Research led by Weizmann Institute scientists shows why leukemia often returns
 

(l-r) Prof. Yosef Yarden and Dr. Yaron Mosesson. In the bubble
Cancer’s Ins and Outs
01.10.2009
Cancer

Cells missing a recycling mechanism get trapped in a cancer-causing cycle

Clinging for Dear Life
Clinging for Dear Life
01.10.2009
Biochemistry
A rare disease sheds light on back-up DNA repair
chemotherapy alters protein levels in cancer cells
Vive la Difference
01.05.2009
Cancer, Molecular and Cell Biology
 
 

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Dumpster Diving in Cancer Tissue Uncovers an Immune Evasion Mechanism

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

Peripheral sensory neurons in a laboratory dish

Unlocking a Secret Nerve Cell Regenerator

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Surviving on an Empty Battery

Press Releases
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A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta
06.09.2023
Human Embryo Models Grown from Stem Cells
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17.08.2023
Surviving on an Empty Battery
14.08.2023
A “Jupiter” Hotter than the Sun
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The Limits of Computing

Computers can solve complex problems but they are far from omnipotent. Prof. Ran Raz of the Weizmann Institute's Computer Science and Applied Mathematics Department is trying to portray the limits...

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