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Cancer cell survival

Combat team: A dendritic cell (right) and a T cell, both from a mouse with skin cancer, combined using the BiCE antibody (yellow)

A new kind of immunotherapy, based on crosstalk between different immune cells, could pave the way for innovative treatments of cancer and...


Cancer alters cellular waste-processing machinery, helping it avoid detection by the immune system

Human lung cancer cells harboring the L858R mutation in the EGFR gene. Cell nuclei are in blue. The red color marks a protein that is present in the cell cytoplasm when the EGFR is active and driving the uncontrolled cell divisions

Weizmann Institute researchers identify a biomarker that may one day enable a subgroup of lung cancer patients to benefit from relapse-free...

Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered

Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to...


How tumors mutate their way out of a crisis – and become drug resistant in the process

Cultured colorectal cancer cells. Top: Cells that have become resistant to certain forms of chemotherapy and continue to thrive. Bottom: The same cells, which have had the LIP gene inserted and are then treated with chemotherapy drugs

What makes cancer cells survive chemotherapy?

Prof. Ehud Shapiro, Dr. Rivka Adar, Adam Spiro and Noa Chapal-Ilani

Do chemotherapy drugs miss a hidden reservoir of cancer cells?

 Leukemia cells. Image: Wikimedia commons, NIH

Research led by Weizmann Institute scientists shows why leukemia often returns

(l-r) Prof. Yosef Yarden and Dr. Yaron Mosesson. In the bubble

Cells missing a recycling mechanism get trapped in a cancer-causing cycle

Clinging for Dear Life
A rare disease sheds light on back-up DNA repair