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Cancer cell survival

Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered
08.02.2023

Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to...

Shutterstock
31.08.2022

How tumors mutate their way out of a crisis – and become drug resistant in the process

Cultured colorectal cancer cells. Top: Cells that have become resistant to certain forms of chemotherapy and continue to thrive. Bottom: The same cells, which have had the LIP gene inserted and are then treated with chemotherapy drugs
02.07.2015

What makes cancer cells survive chemotherapy?

Prof. Ehud Shapiro, Dr. Rivka Adar, Adam Spiro and Noa Chapal-Ilani
17.07.2012

Do chemotherapy drugs miss a hidden reservoir of cancer cells?

 Leukemia cells. Image: Wikimedia commons, NIH
29.05.2012

Research led by Weizmann Institute scientists shows why leukemia often returns
 

(l-r) Prof. Yosef Yarden and Dr. Yaron Mosesson. In the bubble
01.10.2009

Cells missing a recycling mechanism get trapped in a cancer-causing cycle

Clinging for Dear Life
01.10.2009
A rare disease sheds light on back-up DNA repair
How Cancer Cells Survive a Chemotherapy Drug
28.01.2009
What separates the few cancer cells that survive chemotherapy – leaving the door open to recurrence – from those that don’t?...
Prof. Idit Shachar
02.05.2008
Blocking a white blood cell receptor helps leukemia cells die