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migrating cells
The Migration of the Undead
08.11.2018
Biochemistry, Cancer, Systems Biology, Molecular and Cell Biology, Evolution and Development

Sub-lethal levels of a “self-destruct” enzyme hold cells in place

Sperm individualization
Delicate Demolition
19.05.2016
Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Fertility

How does a sperm cell become an "individual?"

 

 

 

The tips of two adult fruit fly testes, viewed under a confocal microscope, are filled with dividing germ cells (green). About one quarter of these germ cells die by an alternative death pathway called germ cell death (pink and red)
Alternate Endings
05.06.2013
Cancer, Molecular and Cell Biology
A newly discovered cell-death pathway could help fight cancer
Programmed Destruction
Programmed Destruction
18.03.2013
Biochemistry, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

Results showing the same signaling enzymes can trigger two different...

Budding wing from irradiated fruit fly larvae, magnified about 80 times; various aspects of apoptosis in a regular fly (left column) are compared with the mutant fly lacking the drice gene (right column). Upper row: “reporter” proteins are highlighted with green fluorescent protein; middle row: the cutting up of these reporter proteins by caspases; bottom row: numerous cells die by apoptosis in the regular fruit fly (left), whereas almost no apoptosis occurs in the fly lacking the Drice caspase (right)
The Slings and Arrows of Outrageous Cellular Fortune
11.06.2012
Cancer, Molecular and Cell Biology

What separates the cells that are prone to suicide from those that are long lived?

cellular steam release valve
Molecular Release Valve
17.08.2011
Biochemistry, Immunology

An inflammatory signal contains its own shut-down mechanism

Immune System Release Valve
Immune System Release Valve
25.05.2011
Biochemistry, Immunology, Disease, Drugs & Diagnostics

Weizmann Institute scientists reveal a new mechanism for keeping inflammation in check
 

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Burning Cancer’s Bridges

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Crystalizing Our Comprehension of Malaria

A tumor sample from a human patient with the most common type of lung cancer (adenocarcinoma). Senescent cells are highlighted by their expression of the p16 (red) and the PD-L1 (green) proteins. Cell nuclei are in blue

Unclogging the Immune System

MRI brain scans of mice with Gaucher disease Type III. The scan of a mouse that received the new treatment (left) shows a significant reduction in tissue inflammation (blue) compared to an untreated mouse (right)

Improving the Recipe for Gene Therapy

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27.08.2024
The Weizmann Institute of Science Ranked among the World’s Top Ten Academic Institutions
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26.08.2024
A Discovery to Set Your Heart a-Knocking
An image of tissue from the human small intestine obtained with the help of fluorescent dyes that made it possible to mark numerous proteins in parallel, thereby mapping out the various proteins produced in each part of the intestinal villi
07.08.2024
Navigating the Digestive Tract
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The Limits of Computing

Computers can solve complex problems but they are far from omnipotent. Prof. Ran Raz of the Weizmann Institute's Computer Science and Applied Mathematics Department is trying to portray the limits...

Let it Rain

Added particles in the atmosphere could be affecting rainfall patterns