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Chemical and Structural Biology

Mucin (magenta) in the inner lining of a mouse colon, viewed under a microscope
Slippery Chaperone: Intestinal Mucus Takes Charge of Copper
01.12.2022
Structural Biology, Biochemistry, Nutrition

Proteins in our “smart slime” take in potentially toxic ions and deliver them safely to cells, Weizmann Institute researchers have shown...

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Origin of Life – In an RNA Pocket
14.09.2022
Organic Chemistry, Structural Biology, Evolution and Development

How did amino acids start bonding to form proteins? Weizmann Institute of Science researchers bring their findings to life in their...

Dr. Nir London
Global Initiative to Rapidly Develop a Safe, Globally Accessible and Affordable COVID-19 Antiviral Pill
29.09.2021
Structural Biology, Disease, Drugs & Diagnostics, Benefiting Humanity, Diagnostic Techniques and Drugs

COVID Moonshot – the world's largest open-science drug discovery effort – aims to identify pre-clinical candidate molecules, with first clinical...

Illustration: Yuval Robichek
Calling through the DNA Wire
05.08.2021
Structural Biology, Viruses & Microorganisms, Genetics

Proteins communicating through the DNA molecule constitute a newly discovered genetic "switch"

Electron microscopy images representing different views of the MC4 receptor bound to setmelanotide, in complex with proteins activated by the binding
The Hunger Games: Uncovering the Secret of the Hunger Switch in the Brain
15.04.2021
Structural Biology, Brain & Behavior, Nutrition, Disease, Drugs & Diagnostics

A 3D structure reveals how a unique molecular switch in our brain causes us to feel full – and may help develop improved anti-obesity drugs...

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Dumpster Diving in Cancer Tissue Uncovers an Immune Evasion Mechanism

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

Peripheral sensory neurons in a laboratory dish

Unlocking a Secret Nerve Cell Regenerator

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Surviving on an Empty Battery

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A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta
06.09.2023
Human Embryo Models Grown from Stem Cells
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17.08.2023
Surviving on an Empty Battery
14.08.2023
A “Jupiter” Hotter than the Sun
Most Popular Articles

One Protein, Two Programs

A cell’s decision to commit suicide involves an exchange of information between two suicide mechanisms

Checking the Dosage

Prof. Yoram Groner is a pioneer in Down syndrome research

The Limits of Computing

Computers can solve complex problems but they are far from omnipotent. Prof. Ran Raz of the Weizmann Institute's Computer Science and Applied Mathematics Department is trying to portray the limits...