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igor Ulitsky

Magnetic resonance imaging (MRI) scans of the brain in three children with a missing copy of the Chaserr gene. The scans performed at age 8 months or 4 years (top row) reveal structural changes in the brain, including reduced volume of the brain stem (asterisks) and decreased myelin coating of nerves (arrows) in deep-seated brain areas. These changes are less apparent at 1 month of age (bottom row)
Emma’s Gene
24.07.2025
Biochemistry, Brain & Behavior, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Scientists discover a rare disorder caused by a missing genetic brake

When the Beads Line Up
When the Beads Line Up
05.04.2021
Bioinformatics and Computational Biology, Systems Biology, Evolution and Development, Genetics

Conserved elements reveal vital spots in the noncoding, regulatory, portions of the genome 

When the NXF1 gene functions properly (left), RNA molecules (orange dots) of a particular single-exon gene are exported from the nucleus (purple) into the cytoplasm; when the NXF1 is silenced (right), the RNAs are largely stuck within the nucleus
Two Roads Diverged in a Cell
28.07.2020
Systems Biology, Viruses & Microorganisms, Molecular and Cell Biology, Genetics

Cells use two separate routes to export RNA out of the nucleus

Dr. Igor Ulitsky
Dr. Igor Ulitsky
29.01.2020

Dr. Igor Ulitsky is the recipient of a Blavatnik Award for Young Scientists in Life Sciences

Humans and fish share about 70% of their protein-coding genes, but only about 0.5% of their regulatory long noncoding RNAs (lncRNAs)
Genomic Recycling: Ancestral Genes Take On New Roles
18.09.2017
Systems Biology, Evolution and Development, Genetics

How some genes lost the ability to make proteins - and gained regulatory powers 

Dr. Igor Ulitsky
Dr. Igor Ulitsky
06.04.2016

...

We share many of our genes with sea urchins, but none of the sequences for long non-coding RNAs that regulate those genes
Looking for Links
25.05.2015
Systems Biology, Molecular and Cell Biology, Evolution and Development, Genetics, Bioinformatics and Computational Biology

Non-coding DNA sequences on an evolutionary “fast track” may hold clues to human disease

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Magnetic resonance imaging (MRI) scans of the brain in three children with a missing copy of the Chaserr gene. The scans performed at age 8 months or 4 years (top row) reveal structural changes in the brain, including reduced volume of the brain stem (asterisks) and decreased myelin coating of nerves (arrows) in deep-seated brain areas. These changes are less apparent at 1 month of age (bottom row)

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16.07.2025
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