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The molecular structure of Spanish flu protein (hemagglutin) bound to a computationally designed protein (green). The designed protein binds the viral protein tightly and with high specificity, blocking the protein's function and neutralizing viral infectivity
Matchmaker
23.05.2012
Biochemistry, Viruses & Microorganisms, Disease, Drugs & Diagnostics, Structural Biology

 A new method of redesigning protein molecules may yield novel drugs.

Prof. Gideon Schreiber
Meetings in the Cell
11.03.2012
Biochemistry

A new technique enables researchers to watch as proteins interact inside living cells

Levodopa in the active site of mitochondrial Phenylalanyl-tRNA synthetase. The lattice is the observed electron density corresponding to the L-Dopa
A Case of Mistaken Identity
04.10.2011
Biochemistry, Brain & Behavior, Disease, Drugs & Diagnostics, Structural Biology

An accidental substitution in a new protein strand can spell disaster

Leptin receptor positive neuron in the mouse hypothalamus
Protein Contributes to Obesity
04.05.2011
Biochemistry, Brain & Behavior, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics
Mice lacking the protein stayed slim, even on a high-fat diet.
Three-dimensional structure of an enzyme, serum paraoxonase (PON1), which has been mutated in the lab of Prof. Dan Tawfik through directed evolution to endow the enzyme with new functions
What Makes Proteins Tick?
30.08.2010
Space & Physics, Biochemistry, Disease, Drugs & Diagnostics

From solving the structure of crystallized proteins to creating computer simulations of protein dynamics, Institute scientists...

Weizmann Institue Scientists Develop a General
Weizmann Institue Scientists Develop a General "Control Switch" for Protein Activity
19.06.2007
Personalized Medicine, Disease, Drugs & Diagnostics, Genetics, Chemistry

 

Prof. Ada Yonath. Trucking with molecules
Bonds
01.05.2007
Biochemistry, Structural Biology
Revealing the details of protein assembly might advance drug development
Profs. Eitan Bibi and Deborah Fass. Working in the wet
An Enzyme out of Water
01.05.2007
Biochemistry, Molecular and Cell Biology, Structural Biology
Proteases shouldn't work in the cell membrane. But they do.
WOWing the Crowds
WOWing the Crowds
01.05.2006
Biochemistry, Technology & Applications

A method based on living cells could speed up protein searchs from years to days

Deciphering Gaucher's Disease
Deciphering Gaucher's Disease
01.10.2003
Biochemistry, Brain & Behavior, Disease, Drugs & Diagnostics, Genetics, Structural Biology

New finding may lead to more effective – and affordable – treatments

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Multiple Proteins Viewed as Never Before

Getting Cancer to Unmask Itself

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They’d Rather Die: The Lesson That Male Roundworms Refuse to Learn

Dr. Omer Kneller (left) and Chen Mor direct a laser beam before it enters the experimental setup. The experiment required a powerful laser beam that could produce exceptionally short, attosecond light pulses. Photo: Noa Yaffe

Matter at the Crossroads

Press Releases
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27.03.2025
Getting Cancer to Unmask Itself
Staphylococcus bacteria
05.03.2025
New Immune Mechanism Revealed in the Cellular Trash
Mouse heart tissue viewed under a microscope
18.02.2025
A Broken Heart: Two Types of Scars, Two Paths to Healing
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The Limits of Computing

Computers can solve complex problems but they are far from omnipotent. Prof. Ran Raz of the Weizmann Institute's Computer Science and Applied Mathematics Department is trying to portray the limits...