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Evolution of a protein


A protein "time machine" reveals how proteins may have evolved 


Weizmann Institute Structural Proteomics scientists are at the cutting edge of the pipeline “from gene to 3D structure”

g-incpm staff

Meet the unique team of experts at the Nancy and Stephen Grand Israel National Center for Personalized Medicine

Ubiquitin, labeled with a fluorescent marker (yellow), has been successfully delivered into cells.

What do proteins look like in their natural environment?

 Inclusion bodies (red) are surrounded by lipid droplets (green)

Drops of fat could be key to keeping nerve cells healthy

Muscle fibers of a fruit fly larva viewed under a confocal microscope: A normal fiber has normally-shaped, properly distributed nuclei (A), whereas the nuclei of fibers with mutated MSP-300 or its interacting proteins Klar and Klaroid are distorted and distributed abnormally (B, C and D)

Why do muscles lose their strength without exercise?

Water dynamics near an enzyme-collagen complex: The rates at which water molecules exchange hydrogen bonds with one another depend on the distance from the active site of the enzyme (gray) and on the type of collagen interacting with the enzyme; the different rates create a gradient of water motions, ranging from extremely fast (red) to very slow (blue and light-blue)

Water molecules in the body keep going after the main reaction is over

Use It or Lose It

Why do muscles lose their strength without exercise?

Dr. Emmanuel Levy

A new study uncovers the cell’s “social network”