Genetics

A tumor sample from a human patient with the most common type of lung cancer (adenocarcinoma). Senescent cells are highlighted by their expression of the p16 (red) and the PD-L1 (green) proteins. Cell nuclei are in blue

Unclogging the Immune System

21.10.2024

Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute researchers reveal how aging cells evade our immune systems – and propose developing an innovative treatment for age-related...

MRI brain scans of mice with Gaucher disease Type III. The scan of a mouse that received the new treatment (left) shows a significant reduction in tissue inflammation (blue) compared to an untreated mouse (right)

Improving the Recipe for Gene Therapy

13.10.2024

Bioinformatics and Computational Biology, Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

An innovative treatment for Gaucher disease has produced promising results in mice, giving hope to patients after decades of research

An image of tissue from the human small intestine obtained with the help of fluorescent dyes that made it possible to mark numerous proteins in parallel, thereby mapping out the various proteins produced in each part of the intestinal villi

Navigating the Digestive Tract

07.08.2024

Nutrition, Molecular and Cell Biology, Genetics

A comprehensive gene expression atlas of the human small intestine uncovers the secrets of nutrient absorption and defense against infection

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The Constant Gardener

10.06.2024

Brain & Behavior, Molecular and Cell Biology, Genetics

Weizmann Institute researchers have discovered a protein that prunes nerve endings, regulating sensitivity to pain

Researchers used color-coded proteins to reveal the identity of the cells in the organoids they produced. In four organoids that simulate the embryo’s central nervous system, the magenta marks proteins associated with the development of the forebrain and the midbrain, the green, the hindbrain and the red, the center of the spinal cord

From Tip to Tail

01.06.2024

Brain & Behavior, Stem Cells, Evolution and Development, Genetics

Researchers from the University of Michigan and the Weizmann Institute develop the first-ever complete central nervous system on a chip; it...

(l-r) Dr. Anat Bahat and Prof. Rivka Dikstein

Toward a Treatment for Huntington’s Disease

26.02.2024

Brain & Behavior, Disease, Drugs & Diagnostics, Genetics, Benefiting Humanity, Diagnostic Techniques and Drugs

Weizmann Institute scientists have discovered two small molecules that can cross the blood-brain barrier in mice, slowing and even reversing the...

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Down the Rabbit Hole

08.02.2024

Math & Computer Science, Bioinformatics and Computational Biology, Stem Cells, Evolution and Development, Genetics

An innovative Weizmann Institute system for tracking the earliest stages of embryonic development, applied for the first time in rabbits, could...

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There’s a New Hypothesis on Your Hypophysis

02.02.2024

Brain & Behavior, Evolution and Development, Genetics

Weizmann Institute study challenges an old dogma regarding the pituitary gland’s embryonic origins and may lead to new insights into growth hormone...

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

06.09.2023

Stem Cells, Molecular and Cell Biology, Evolution and Development, Fertility, Genetics

The complete, day 14 synthetic models may open new avenues of research into infertility, drug testing and growth of tissues for transplant – as well...

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Surviving on an Empty Battery

17.08.2023

Viruses & Microorganisms, Molecular and Cell Biology, Immunology, Evolution and Development, Genetics

A newly discovered immune strategy protects bacteria and more advanced species, from corals to bees

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Shedding Light on the Dark Hours

Credit: Coleen Murphy, Princeton University, Princeton, NJ

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“Eight Shining Examples of Excellence”

The Weizmann Institute of Science Ranked among the World’s Top Ten Academic Institutions

A Discovery to Set Your Heart a-Knocking