Life Sciences

Pre-leukemic stem cells (top) with both mutated and healthy copies of the RUNX1 gene already display some of the characteristics of acute myeloid leukemia (AML). When the non-mutated copy of the gene is inactivated, disruptions in the spindle-assembly-checkpoint phase of cell division trigger cell death

Leukemia Cells are Addicted to a Healthy Gene

29.09.2013

Cancer, Personalized Medicine, Molecular and Cell Biology, Genetics

Weizmann Institute researchers discover that a “standoff” between a mutated gene and its normal counterpart keeps certain cancer cells alive

Left column: Previous method for creating induced pluripotent stem cells (iPSCs); right column: iPSCs produced with the new method developed by Dr. Hanna. Top: Skin cells (red); center: iPSCs from skin cells (green); bottom: superimposed top and center images. Skin cells that have been reprogrammed into iPSCs appear light yellow. Only a small percentage of the cells on the left have been reprogrammed, in contrast with the high success rate seen with the new method on the right

Stem Cell Reprogramming Made Easier

17.09.2013

Stem Cells, Molecular and Cell Biology, Genetics

Weizmann Institute scientists show that removing one protein from adult cells enables them to efficiently turn back the clock to a stem-cell-like...

Bacterial colonies that express different metabolites

Tuning a Genetic Orchestra

17.09.2013

Biochemistry, Molecular and Cell Biology, Genetics, Plants and Agriculture

Getting bacteria to produce an algal substance means adjusting an entire gene network

colorful roots

Getting to the Root of the Problem

15.09.2013

Biochemistry, Nutrition, Molecular and Cell Biology, Genetics, Plants and Agriculture

Detailed profiles of hundreds of substances produced in different plant cell types can help improve crops – and our health

Without the c-Kit gene, colon cancer cells grow in a disorderly, aggregated manner and are invasive (A); when c-Kit expression is restored in these cells, they revert to a more normal organization (B)

The Double Life of a Cancer Gene

15.09.2013

Space & Physics, Cancer, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A cancer-causing gene can prevent the deadly spread of a tumor at a later point in malignancy

SEM image of the dense microbial ecosystem overlying the 'hilly' gastrointestinal epithelial layer

The Second Genome

08.09.2013

Viruses & Microorganisms, Immunology, Disease, Drugs & Diagnostics, Genetics

Our complicated relationship with the microorganisms in our gut has some surprising consequences for our health

The movements of mice dyed in different fluorescent colors are tracked in the darkened enclosure

Mouse Groups Reveal Complex Relationships

02.09.2013

Brain & Behavior

Mice living together exhibited a social structure based on multiple-level interactions

Where Lab and Clinic Meet- Dr. Ayelet Erez Work

Where Lab and Clinic Meet

02.09.2013

Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics

Dr. Ayelet Erez finds that clinical work and lab research are a powerful combination

potato sprout. Image: Thinkstock

The Pathway to Potato Poisons

31.07.2013

Molecular and Cell Biology, Plants and Agriculture

Revealing the gene network for producing the toxin in green potatoes may help improve crops

Gene Decoding Obeys Road Traffic Rules

Gene Decoding Obeys Road Traffic Rules

31.07.2013

Biochemistry, Molecular and Cell Biology, Genetics

Keeping a proper distance between "vehicles" along a gene "track" results in more efficient production of small RNA molecules

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Dendrites that developed in a tin battery, seen under an electronic microscope. Source: Shakked Schwartz and Ayan Maity

On the Way to Building Better Batteries

Weizmann Institute of Science Moves to 100% Green Electricity

Ants vs. Humans: Putting Group Smarts to the Test

Shedding Light on the Dark Hours

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Weizmann Institute of Science Moves to 100% Green Electricity

Ants vs. Humans: Putting Group Smarts to the Test

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