Bone formation

skeletons

Thinking outside the Skeleton

02.11.2017

Biochemistry, Disease, Drugs & Diagnostics, Evolution and Development, Genetics

Scoliosis may be linked to problems with our "sixth sense"

Bones of mice at different ages, imaged with three-dimensional computer tomography. A core element at the center of the bone (highlighted in different colors) enabled the scientists to align different bones for comparison

Bones Don’t Get the Drift

19.12.2015

Evolution and Development

How do bones retain their proportions as they grow?

$Natural healing process of fractured bones. (A) Healing begins with a collection of blood and inflammation at the fracture site. (B) Soft callus (purple) is formed, which develops into the bidirectional growth plate at the concave side of the fracture site. (C) The growth plate drives bone growth in opposite directions. The result is a jack-like mechanical effect that moves the fragments toward straightening (red arrows). (D) New bone tissue is formed (orange). (E) The shape of the bone is fine-tuned by rem$

Bone: Heal Thyself

04.11.2014

Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Movement might actually help heal fractures in young bones

Developing bone in normal (top) and mutant (bottom) embryos. Protrusions in a developing bone are formed by a distinct class of cells (green) that differ from the regular bone-forming cells (yellow-orange). Incorrect regulation and distribution of these cells leads to irregularities in the shape of the forming bone

The Collagen Paradox

12.02.2014

Stem Cells, Molecular and Cell Biology, Genetics

How does an oxygen-demanding biological process cope with low-oxygen conditions?

All Together Now

All Together Now

09.02.2014

Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics

How do animal embryos take up all the calcium they need to build skeletons, shells or spines?

How Tendons Shape Developing Bones

How Tendons Shape Developing Bones

14.01.2010

Evolution and Development

Bones, muscles and tendons work together to provide the perfect balance between stability and movement in the...

(l-r) Profs. Stephen Weiner and Lia Addadi and Julia Mahamid. Like shell, like bone

Turning to Bone

01.05.2009

Biochemistry, Structural Biology

Scientists reveal a fleeting stage of bone formation

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