Immunology

Dr. Ido Amit

The Gene Control Hierarchy

29.11.2012

Personalized Medicine, Molecular and Cell Biology, Immunology, Genetics

A new, automated method for mapping protein-DNA interactions may lead to advances in personalized medicine

Prostaglandins guard stem cells by increasing the production of an inhibitory factor in the mesenchymal bone marrow cells. Mesenchymal cells are marked with a green protein (left); the inhibitory factor is red (center). Combined image (right): Treatment with prostaglandins (bottom) increases the secretion of the inhibitory factor

How Stem Cells Stay Young

29.11.2012

Cancer, Stem Cells, Immunology, Disease, Drugs & Diagnostics

A rare subgroup of immune cells act as stem cell “bodyguards”

Dr. Nir Friedman

Immune Cells’ Flexible Choices

18.11.2012

Immunology, Genetics

Some immune receptors are created from random combinations of genes. But not everything is left to chance.

Prostaglandins guard stem cells by increasing the production of an inhibitory factor in the mesenchymal bone marrow cells. Mesenchymal cells are marked with a green protein (left); the inhibitory factor is red (center). Combined image (right): Treatment with prostaglandins (bottom) increases the secretion of the inhibitory factor

Stem Cell Bodyguards

22.10.2012

Immunology, Disease, Drugs & Diagnostics

Insights into rare immune cells that keep blood stem cells in a youthful state may lead to better treatments

Immune Cells Make Flexible Choices

Immune Cells Make Flexible Choices

22.10.2012

Immunology, Genetics

Certain immune cell receptors are more common than mere chance would dictate. New research shows why

cell and numbers. Image: Thinkstock

Weizmann Institute’s Mathematical Model May Lead to Safer Chemotherapy

12.09.2012

Cancer, Viruses & Microorganisms, Immunology, Disease, Drugs & Diagnostics, Bioinformatics and Computational Biology

The study explains why certain patients develop severe infections after chemotherapy and points to ways of averting this side-effect

Regulatory factor hierarchy: The highest level (top) determines a cell’s basic identity; the second (middle) shapes its properties; the third (bottom) activates genes according to changing conditions

Uncovering the Genome’s Regulatory Code

09.09.2012

Personalized Medicine, Molecular and Cell Biology, Immunology, Genetics

A new, automated method for mapping protein-DNA interactions may lead to advances in personalized medicine

Electron micrograph of bacteriophages Image: Dr Graham Beards, Wikimedia Commons

Helpful Bacteria, Harmful Viruses

17.07.2012

Viruses & Microorganisms, Immunology, Disease, Drugs & Diagnostics, Genetics

The beneficial bacteria in our guts are open to attack from viruses

Left: Natural control mechanism blocks the enzyme's zinc active site. Right: Novel antibody works as effectively as the natural control mechanism

Immune System Tricks

19.03.2012

Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Structural Biology

A synthetic molecule causes a useful immune response in mice

Electron microscope image of an effector cell inserting several appendages through endothelial cell membranes

Hidden Passage

30.01.2012

Cancer, Molecular and Cell Biology, Immunology

Hidden “exit signs” ensure that only certain white blood cells can find them.

Pages

Top Stories

The Protein Wears Prada

Look on the Bright Side of Earth

Born Ready for Pressure

An illustration showing four modular enzyme fragments (highlighted) that Weizmann Institute’s CADENZ method can combine to generate active enzymes at a hitherto unseen rate

Building Better Enzymes – by Breaking Them Down

Press Releases

Look on the Bright Side of Earth

Building Better Enzymes – by Breaking Them Down

Expanding the Limits of the Possible