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Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered

Thugs in the Cellular Neighborhood

08.02.2023
Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics
Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to recruitment of...
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The Protein Wears Prada

26.01.2023
Cancer, Personalized Medicine, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Technology & Applications, Biotechnology, Diagnostic Techniques and Drugs
A new computational method that tracks multiple protein modifications promises to shed new light on unsolved biomedical problems  
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Born Ready for Pressure

18.01.2023
Brain & Behavior, Molecular and Cell Biology, Evolution and Development
Stress-resilient fish are born that way; their immune system reveals why
An illustration showing four modular enzyme fragments (highlighted) that Weizmann Institute’s CADENZ method can combine to generate active enzymes at a hitherto unseen rate

Building Better Enzymes – by Breaking Them Down

12.01.2023
Bioinformatics and Computational Biology, Biochemistry, Evolution and Development, Environment, Energy, Plants and Agriculture, Climate, Benefiting Humanity, Biotechnology
In a major step toward greener industry, Weizmann Institute scientists create a computational method for generating enzymes with unprecedented...
Seeing Things Differently: The Secret Life of Our Eyes

Seeing Things Differently: The Secret Life of Our Eyes

26.12.2022
Math & Computer Science, Robotics and Machine Learning, Computer Vision, Brain & Behavior
Tracking our eyes’ motion when we are faced with a visual challenge may help researchers uncover neural encoding in the brain
Tiny droplets formed by peptides and RNA, viewed under a microscope

Life’s Mysteries Converge in a Droplet

06.12.2022
Organic Chemistry, Evolution and Development
Recreating conditions that may have existed before the dawn of life, researchers watched droplets give rise to possible precursors of today’s...
Mucin (magenta) in the inner lining of a mouse colon, viewed under a microscope

Slippery Chaperone: Intestinal Mucus Takes Charge of Copper

01.12.2022
Structural Biology, Biochemistry, Nutrition
Proteins in our “smart slime” take in potentially toxic ions and deliver them safely to cells, Weizmann Institute researchers have shown
Down to the Synapse: Connecting Brain Circuits to Behavior

Down to the Synapse: Connecting Brain Circuits to Behavior

15.11.2022
Brain & Behavior
By flipping a single synaptic connection in a neural circuit, the researchers caused male worms to behave like females in response to a painful cue
Bacteriophages attacking a bacterium. Source: Prof. Graham Beards

Viruses Gain the Upper Hand

25.10.2022
Viruses & Microorganisms, Molecular and Cell Biology, Evolution and Development, Genetics
Weizmann Institute scientists reveal how viruses outwit cellular immune systems
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Human Tumors Are Prized Real Estate for Fungi, Study Finds

29.09.2022
Cancer, Personalized Medicine, Viruses & Microorganisms
The findings demonstrate that fungi are living in tumors and may facilitate cancer detection, diagnosis and perhaps even treatment

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Dumpster Diving in Cancer Tissue Uncovers an Immune Evasion Mechanism

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

Peripheral sensory neurons in a laboratory dish

Unlocking a Secret Nerve Cell Regenerator

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Surviving on an Empty Battery

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A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta
06.09.2023
Human Embryo Models Grown from Stem Cells
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17.08.2023
Surviving on an Empty Battery
14.08.2023
A “Jupiter” Hotter than the Sun