Life Sciences

Having Their Fortress and Leaving It Too

Having Their Fortress and Leaving It Too

18.08.2020

Viruses & Microorganisms

Humble amyloids have many uses – for bacteria, at least – aiding both migration and antibiotic resistance

Reprogrammed cells: β cells expressing insulin (green) and the closely related δ cells expressing somatostatin (red). Blue staining shows cell nuclei. Many reprogrammed cells contain two nuclei (a unique feature of some exocrine cells) demonstrating their exocrine cell origin

No REST for Beta Cells

18.08.2020

Stem Cells, Molecular and Cell Biology, Disease, Drugs & Diagnostics

Why is reprogramming cells to cure diabetes so difficult?

pain response

Targeting a Chronic Pain Gateway Could Bring Relief

14.08.2020

Biochemistry, Personalized Medicine, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Diagnostic Techniques and Drugs

A new approach to chronic pain treatment targets a molecule that moves pain messages into nerve cell nuclei

One-Sided Memories and Sleep

One-Sided Memories and Sleep

03.08.2020

Brain & Behavior

A unique sleep experiment to uncover brain activity comes up smelling of roses

pregnant belly with mask on

Not Just Infection: Pregnant Women’s Immune Response to a Virus May Affect Fetal Brain Cells

30.07.2020

Brain & Behavior, Viruses & Microorganisms

In a study in mice, the mother’s natural anti-viral proteins disrupted the development of neural circuits in the fetus

contract sign

Weizmann Institute of Science and Schneider Children’s Medical Center of Clalit Health Services to Collaborate

30.07.2020

Life Sciences, Personalized Medicine

The two aim to establish the Schneider-Weizmann Center for Research on Child and Adult Health

When the NXF1 gene functions properly (left), RNA molecules (orange dots) of a particular single-exon gene are exported from the nucleus (purple) into the cytoplasm; when the NXF1 is silenced (right), the RNAs are largely stuck within the nucleus

Two Roads Diverged in a Cell

28.07.2020

Systems Biology, Viruses & Microorganisms, Molecular and Cell Biology, Genetics

Cells use two separate routes to export RNA out of the nucleus

Tissue sample from triple-negative breast cancer, stained for the presence of cancer cells (red) and the two types of cancer-associated fibroblasts: pCAFs (magenta) and sCAFs (green). The nuclei of all cells are stained blue

Cancer “Helpers” Come in Different Types

23.07.2020

Biochemistry, Cancer, Personalized Medicine

Supporting actors in cancer growth may help predict the course of the disease

Fluorescent image of artificial cells on a chip. The differences in genetic composition between cells produced the different colors, which reveal stages in building parts of a virus

Artificial Cells Produce Parts of Viruses for Safe Studies

20.07.2020

Nanoscience, Materials Science, Viruses & Microorganisms, Diagnostic Techniques and Drugs

The Weizmann Institute of Science group demonstrated the production of protein assembly lines on a silicon chip

Lung cancer samples: Far left untreated. Lung cancer tissue failed to respond when exposed to a microtubule inhibitor drug (left) or to a drug that enhanced the apoptosis-inducing pathway (middle). But when the two drugs were applied together to the same tissue, the cancer cells died (right)

A New Approach to Tailoring Cancer Therapy: Tapping into Signaling Activities in Cancer Cells

16.07.2020

Cancer, Personalized Medicine, Systems Biology, Disease, Drugs & Diagnostics

Matching drugs to tumors may lead to personalized treatment and new therapies

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