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(l-r) Profs. Stephen Weiner and Lia Addadi and Julia Mahamid. Like shell, like bone

Turning to Bone

01.05.2009
Biochemistry, Structural Biology
Scientists reveal a fleeting stage of bone formation
DNA invades the host cell through a star-shaped opening

Large-Scale Invasion

01.11.2008
Viruses & Microorganisms, Structural Biology
A giant virus must be efficient to get its DNA into the host cell
The enzyme’s structure (blue), revealed via X-ray crystallography, closely matches its computer design (gray). The yellow structure in the center is the substrate molecule the enzyme acts upon

Winning Design

01.10.2008
Biochemistry, Structural Biology
Evolution in a test tube takes enzyme design to a new level
The ISPC team: Standing (l-r) Dr. Harry Mark Greenblatt, Dr. Jaime Prilusky, Prof. Yigal Burstein, Prof. Israel Silman, Dr. Tamar Unger, Dr. Orly Dym, Dr. Yoav Peleg and Anat Kats. Middle (l-r) David Mualem, Anna Branzburg-Mualem, ISPC Head Prof. Joel L. Sussman, Prof. Gideon Schreiber, Meital Rubin-Yona and Ada Dantes. Front (l-r) Dr. Shira Albeck, Rani Bravdo, Reut Rotem-Bernehim, Moshe Ben David and Bracha Vakni.

By Its Shape

01.10.2008
Molecular and Cell Biology, Genetics, Structural Biology
The Israel Structural Proteomics Center deciphers over 40 proteins in five years
Prof. Irit Sagi

Designer Drugs

31.08.2008
Cancer, Structural Biology
This antibody might be used to create a new drug against metastatic cancer and autoimmune diseases
Structural model of an MMP-9 enzyme

The Weak Link

02.05.2008
Structural Biology
The Achille's heel of an enzyme involved in cancer metastasis is revealed  
Dr. Nir Gov. The physics of fingers, hair and spines

Living Force

01.05.2008
Space & Physics, Structural Biology
Physics helps explain the formation of spines and bumps on specialized cells   
Prof. Osnat Herzberg

Crystal Clear

01.05.2008
Disease, Drugs & Diagnostics, Structural Biology
An Institute alumna returns on sabbatical  
Birth of an Enzyme

Birth of an Enzyme

24.03.2008
Biochemistry, Genetics, Structural Biology
Scientists succeed in designing artificial enzymes that also undergo 'evolution in a test tube'   Mankind triumphed in a recent 'competition'...
A(l-r) Prof. Irit Sagi, Barak Akabayov and Ariel Solomon.

Step by Step

01.10.2007
Disease, Drugs & Diagnostics, Structural Biology
A technique for observing rapid enzyme movements in real time may help in developing better drugs

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An electron microscope view of phages duplicated inside bacterial cells that possess the immune system discovered in the new study. This immune system attaches a ubiquitin-like protein (marked by black dots and white arrows) to the tails of these phages, preventing them from infecting other bacterial cells

Catch a Virus by Its Tail

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Sticking a Pin in Cancer

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