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Biomolecular Sciences

Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered

Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to...

An illustration showing four modular enzyme fragments (highlighted) that Weizmann Institute’s CADENZ method can combine to generate active enzymes at a hitherto unseen rate

In a major step toward greener industry, Weizmann Institute scientists create a computational method for generating enzymes with unprecedented...

Tiny droplets formed by peptides and RNA, viewed under a microscope

Recreating conditions that may have existed before the dawn of life, researchers watched droplets give rise to possible precursors of today’s...

Dr. Shiran Barber-Zucker and Prof. Sarel Fleishman. Protein Goldmine

Forget crystals. AI gives Weizmann’s algorithms the means to design biomolecules with a huge range of valuable functions

Jam session. Source: Shutterstock

How are the body’s day-night cycles orchestrated between different organs, tissues and cells? 

New York City. Image: Shutterstock

Tracing the evolution of protein maintenance in cellular "boroughs...

The image that appeared on the publishing journal's cover

The secrets of “professional secretor” cells: how they stay in shape

SARS-CoV-2 infected cells

How SARS-CoV-2 jams an important cellular communications channel and what can be done to restore it

Illustration of SARS-CoV-2 attaching to an ACE2 receptor located on the host cell's membrane. Source: Shutterstock

Therapeutic approach developed by Weizmann Institute scientists could spell new hope in the battle against COVID-19