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Eytan Domany

Prof. Eytan Domany

Prof. Eytan Domany is the recipient of the Levi-Montalcini Prize from the Italian government.

Gene expression of schizophrenia-related genes. 1,028 genes with very similar expression profiles are shown, one to a row, and 480 samples are arrayed in the columns. Red-to-blue shows the strength of the gene's expression level, red being stronger

New research reveals a cluster of genetic “typos” that may increase the risk of schizophrenia

NPM1 interacts with DNA polymerase eta and regulates polymerase eta-promoted TLS. Assay of polymerase eta and NPM1 in unirradiated (l) and ultraviolet irradiated cells ((c) after one hour, (r) after 18 hours). Blue: DNA in the nucleus; green: polymerase eta–NPM1 interaction

A mechanism for keeping DNA repair mistakes to a minimum might advance the development of cancer drugs


receptors day and night

Weizmann Institute scientists reveal that a hormone that keeps us alert also suppresses the spread of cancer

Without the c-Kit gene, colon cancer cells grow in a disorderly, aggregated manner and are invasive (A); when c-Kit expression is restored in these cells, they revert to a more normal organization (B)

A cancer-causing gene can prevent the deadly spread of a tumor at a later point in malignancy

Dr. Danny Kandel

Dr. Danny Kandel, Senior Director of Advanced Development for KLA-Tencor, Israel, develops ultra-precise measurement systems

“Deregulation scores” of hundreds of brain tumor patients: Each row corresponds to a pathway (that is, a biochemical process), and each column to a sample taken from a patient. Every colored spot stands for a number – the value of the “deregulation score” of the corresponding pathway, as determined for a particular patient. Dark blue stands for the activity of the pathway in normal brain tissue, whereas dark red indicates a high level of deviation from normal behavior. The clearly distinct group of normal b

A new approach to personalized cancer therapy profiles a tumor by its biological pathways

Drs. Yotam Drier (left) and Gad Getz at the Broad Institute

A unique collaboration is helping map out the genetics of cancer

Stem cells (alkaline phosphatase staining) from the lab of Dr. Jacob Hanna

When a critical step in stem cell differentiation goes awry, it can lead to cancer

Judging DNA by Its Cover

A newly-discovered molecular mechanism might explain the link between stem cells and cancer