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fruit fly larval salivary gland
How Cells Spit It Out
01.01.2016
Biochemistry, Molecular and Cell Biology, Genetics, Structural Biology

How do the cells that secrete saliva or tears handle the load? 

The tips of two adult fruit fly testes, viewed under a confocal microscope, are filled with dividing germ cells (green). About one quarter of these germ cells die by an alternative death pathway called germ cell death (pink and red)
Alternate Endings
05.06.2013
Cancer, Molecular and Cell Biology
A newly discovered cell-death pathway could help fight cancer
Inherited expression levels of the resistance gene (green) and the native gene (red), shown in the stomachs of unchallenged larva (left), challenged larva (center) and unchallenged larval offspring of challenged larvae, eight generations later (right)
Adapting on the Fly
01.08.2012
Biochemistry, Evolution and Development, Genetics

Can a genetic response to a short-term threat be inherited over the long term?

Profs. Bernardo Vidne and Talila Volk. From human hearts to fruit fly hearts
Heart and Mind
02.04.2012
Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics, Science Teaching

After a career as a top cardiac surgeon, Prof. Bernardo Vidne decided to get a Ph.D. in science

The adult stem cell unit: Niches are in red. Cap cells (barbed arrowhead) are tightly associated with germ-line stem cells (outlined). Germ-line stem cells carry a spherical organelle - a fusome - which is asymmetrically localized to the side of the cap cells (arrow). Once the stem cell divides, one daughter cell loses contact with the niche and differentiates (green). The fusome in a differentiating germ cell becomes branched (arrowhead)
Stem Cell Phone Home
18.12.2011
Stem Cells, Molecular and Cell Biology

Nature has an ingenious method for orchestrating stem cell development.

The patterns on these butterfly wings are perfectly scaled, even though they are different sizes
Built to Scale
04.10.2011
Molecular and Cell Biology, Evolution and Development, Genetics

How does a growing, developing organism keep everything in proportion?

Scale Models
Scale Models
22.08.2011
Molecular and Cell Biology, Evolution and Development, Genetics

How do organisms keep everything in proportion as they grow and develop?

A developing eye of the fruit fly (left) is connected by the optic stalk to the optic lobe in the fly’s brain
Take the Axon Train
14.03.2011
Brain & Behavior, Molecular and Cell Biology, Genetics

Institute scientists discover an entirely new form of transportation inside nerve cells

(l-r) Dr. R’ada Massarwa, Prof. Ben-Zion Shilo and Dr. Eyal Schejter. On the secreting edge
The Organ Underground
01.10.2009
Molecular and Cell Biology
A unique cable system directs substances to the exits of secretory cells
Dr. Lilach Gilboa. The nature of the niche
The Origin of the Cell
01.05.2009
Cancer, Molecular and Cell Biology

The ovaries of fruit fly larvae hold clues to basic principles of development, stem cells and cancer

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Credit: Coleen Murphy, Princeton University, Princeton, NJ

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