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Fruit fly

fruit fly larval salivary gland

How do the cells that secrete saliva or tears handle the load? 

The tips of two adult fruit fly testes, viewed under a confocal microscope, are filled with dividing germ cells (green). About one quarter of these germ cells die by an alternative death pathway called germ cell death (pink and red)
A newly discovered cell-death pathway could help fight cancer
Inherited expression levels of the resistance gene (green) and the native gene (red), shown in the stomachs of unchallenged larva (left), challenged larva (center) and unchallenged larval offspring of challenged larvae, eight generations later (right)

Can a genetic response to a short-term threat be inherited over the long term?

Profs. Bernardo Vidne and Talila Volk. From human hearts to fruit fly hearts

After a career as a top cardiac surgeon, Prof. Bernardo Vidne decided to get a Ph.D. in science

The adult stem cell unit: Niches are in red. Cap cells (barbed arrowhead) are tightly associated with germ-line stem cells (outlined). Germ-line stem cells carry a spherical organelle - a fusome - which is asymmetrically localized to the side of the cap cells (arrow). Once the stem cell divides, one daughter cell loses contact with the niche and differentiates (green). The fusome in a differentiating germ cell becomes branched (arrowhead)

Nature has an ingenious method for orchestrating stem cell development.

The patterns on these butterfly wings are perfectly scaled, even though they are different sizes

How does a growing, developing organism keep everything in proportion?

Scale Models

How do organisms keep everything in proportion as they grow and develop?

A developing eye of the fruit fly (left) is connected by the optic stalk to the optic  lobe in the fly’s brain

Institute scientists discover an entirely new form of transportation inside nerve cells

(l-r) Dr. R’ada Massarwa, Prof. Ben-Zion Shilo and Dr. Eyal Schejter. On the secreting edge
A unique cable system directs substances to the exits of secretory cells
Dr. Lilach Gilboa. The nature of the niche

The ovaries of fruit fly larvae hold clues to basic principles of development, stem cells and cancer