Biochemistry

bone loss_galectin

A Hitchhiker’s Guide to the Galectins

13.07.2015

Biochemistry, Molecular and Cell Biology, Disease, Drugs & Diagnostics

A protein ties osteoporosis to high blood sugar and the spread of cancer to the bone

Inclusion bodies (red) are surrounded by lipid droplets (green)

A Cellular “Detergent” Cleans Unsightly Clumps

27.05.2015

Biochemistry, Brain & Behavior, Molecular and Cell Biology

Drops of fat could be key to keeping nerve cells healthy

A partially unfolded protein (yellow) is broken down by a “scissor”-proteasome (blue and red)

Molecules of the Latest Cut

11.05.2015

Biochemistry, Cancer, Molecular and Cell Biology, Genetics

Understanding how a pair of molecular “scissors” are kept in check may help treat disease

Water dynamics near an enzyme-collagen complex: The rates at which water molecules exchange hydrogen bonds with one another depend on the distance from the active site of the enzyme (gray) and on the type of collagen interacting with the enzyme; the different rates create a gradient of water motions, ranging from extremely fast (red) to very slow (blue and light-blue)

It Ain’t Over Till It’s Over

04.02.2015

Water molecules in the body keep going after the main reaction is over

NPM1 interacts with DNA polymerase eta and regulates polymerase eta-promoted TLS. Assay of polymerase eta and NPM1 in unirradiated (l) and ultraviolet irradiated cells ((c) after one hour, (r) after 18 hours). Blue: DNA in the nucleus; green: polymerase eta–NPM1 interaction

Living with the Quick Fix

29.12.2014

Biochemistry, Cancer, Molecular and Cell Biology, Genetics

A mechanism for keeping DNA repair mistakes to a minimum might advance the development of cancer drugs

YEDA-XL-Protein GmbH Agreement

YEDA-XL-Protein GmbH Agreement

21.10.2014

Biochemistry, Immunology, Disease, Drugs & Diagnostics

Combining two technologies makes a drug compound stronger and longer-lasting

(l-r) Drs. Yael Elbaz-Alon and Maya Schuldiner

Contacts

03.08.2014

Biochemistry, Molecular and Cell Biology

A cellular organelle reveals a surprising backup resource for obtaining important building materials

how the IFN Antagonist Affects Type 1 IFN responses to pathogens

Interfering with Interferon

28.07.2014

Biochemistry, Viruses & Microorganisms, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

Virus-killing molecules may need all their skills, including inflammation, to fight HIV infection

Cytoskeletal fibers (green) and adhesion sites (orange) grow when the Arp2/3 complex is present in its hybrid version (right) compared with the regular, seven-subunit version (left). When Arp2/3 is absent altogether, the fibers and the adhesion sites deteriorate (center)

When the Reshaping Tool Reshapes Itself

19.05.2014

Biochemistry, Molecular and Cell Biology

A seven-unit structure that helps a cell move can rearrange to help anchor it in place

DNA repair mechanism. Image: Wikimedia Commons

Risk Assessment

28.04.2014

Biochemistry, Cancer, Personalized Medicine, Disease, Drugs & Diagnostics, Genetics

A combined DNA repair score can reveal an individual’s chances of developing lung cancer

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Top Stories

Staphylococcus bacteria

New Immune Mechanism Revealed in the Cellular Trash

When Proteins Go on Strike

Mouse heart tissue viewed under a microscope

A Broken Heart: Two Types of Scars, Two Paths to Healing

Seeding the Passion

Press Releases

New Immune Mechanism Revealed in the Cellular Trash

A Broken Heart: Two Types of Scars, Two Paths to Healing

Training Future Physician-Scientists: The Weizmann Institute Receives Approval for a New Medical School