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Human lung cancer cells harboring the L858R mutation in the EGFR gene. Cell nuclei are in blue. The red color marks a protein that is present in the cell cytoplasm when the EGFR is active and driving the uncontrolled cell divisions

A Select Group: Study May Bring Improved Therapy to Preselected Lung Cancer Patients

08.08.2023
Cancer, Personalized Medicine, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics
Weizmann Institute researchers identify a biomarker that may one day enable a subgroup of lung cancer patients to benefit from relapse-free treatment
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Why Do Cancer Patients Lose So Much Weight?

08.05.2023
Cancer, Nutrition, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics
Wasting syndrome – a deadly cancer side-effect – might be diagnosed and treated early on, according to a new study
Tissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple); cell nuclei are in blue

Immunotherapy Drugs Step on the Gas

05.03.2023
Cancer, Personalized Medicine, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Diagnostic Techniques and Drugs
Sometimes anticancer antibodies press on the gas and the brakes at the same time. New research might help them accelerate better
Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered

Thugs in the Cellular Neighborhood

08.02.2023
Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics
Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to recruitment of...
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The Protein Wears Prada

26.01.2023
Cancer, Personalized Medicine, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Technology & Applications, Biotechnology, Diagnostic Techniques and Drugs
A new computational method that tracks multiple protein modifications promises to shed new light on unsolved biomedical problems  
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Human Tumors Are Prized Real Estate for Fungi, Study Finds

29.09.2022
Cancer, Personalized Medicine, Viruses & Microorganisms
The findings demonstrate that fungi are living in tumors and may facilitate cancer detection, diagnosis and perhaps even treatment
Patterns of epigenetic markers revealed by EPINUC on blood nucleosomes (bright-red dots)

Putting Liquid Biopsies on Solid Ground: Cancer Diagnosis from a Milliliter of Blood

08.09.2022
Cancer, Personalized Medicine, Disease, Drugs & Diagnostics, Benefiting Humanity, Biotechnology, Diagnostic Techniques and Drugs
If larger studies confirm the results of a Weizmann Institute innovation, diagnosing cancer may one day be as easy as taking blood  
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Desperate Cancer Cells

31.08.2022
Cancer, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics
How tumors mutate their way out of a crisis – and become drug resistant in the process
Natural anticancer antibodies (green) bound to a single ovarian tumor cell; the cell’s nucleus is in blue. Viewed with confocal microscopy

Antibodies Fight Cancer Too

23.03.2022
Cancer, Personalized Medicine, Immunology, Disease, Drugs & Diagnostics
Natural antibodies found in tumors could point the way toward improved immunotherapy 
(l-r) Dr. Ashish Noronha, Prof. Yosef Yarden, and Dr. Nishanth Belugali Nataraj

To Slow Cancer, Close the Cells’ Tunnels

22.02.2022
Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics
A gene for transport helps aggressive cancer cells move and spread 

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