Cancer

Cultured colorectal cancer cells. Top: Cells that have become resistant to certain forms of chemotherapy and continue to thrive. Bottom: The same cells, which have had the LIP gene inserted and are then treated with chemotherapy drugs

Opposite Effects

02.07.2015

Cancer, Molecular and Cell Biology

What makes cancer cells survive chemotherapy?

Normal human colonic crypts. SMOC-2 expression (red) in the colonic stem cells demonstrates that these cells are localized in the bottoms of the crypts. Bars represent 100 micrometers (left) and 50 micrometers (right)

Colon Cancer: Taking a Step Back to Move Forward

29.06.2015

Cancer, Stem Cells, Molecular and Cell Biology

Some tumor cells in the advanced stages of colorectal cancer adopt a less mature, more stem-like, state that assists metastasis

A melanoma cancer cell is labeled with invadopodia markers in fluorescence microscopy

Support for an Invasion

14.06.2015

Cancer, Molecular and Cell Biology

How does a cancer cell push its way out of the surrounding tissue?

Prof. Zelig Eshhar

Prof. Zelig Eshhar

27.05.2015

Cancer, Personalized Medicine, Nutrition, Stem Cells, Systems Biology, Viruses & Microorganisms, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

Prof. Zelig Eshhar

A partially unfolded protein (yellow) is broken down by a “scissor”-proteasome (blue and red)

Molecules of the Latest Cut

11.05.2015

Biochemistry, Cancer, Molecular and Cell Biology, Genetics

Understanding how a pair of molecular “scissors” are kept in check may help treat disease

Immortalized cells, left, pretreated with a drug that blocks the ERK signal, and right, without the pretreatment. Top cells are untreated, while the bottom ones are stimulated

To Stop Cancer: Block its Messages

30.03.2015

Cancer, Disease, Drugs & Diagnostics

Weizmann Institute scientists identify a potential drug molecule that stops cancer cells, but not healthy ones, from getting their “mail”

Prof. Lea Eisenbach

Cold War against Cancer

11.03.2015

Combining two innovative treatments might help keep cancer from spreading

A metastatic breast cancer cell under a fluorescent microscope.

Victory in Numbers

23.02.2015

Cancer, Genetics

The discovery of a new breast cancer gene holds hope for treatment

(l-r) bottom: Tamar Gross, Prof. Lea Eisenbach, Dr. Esther Tzehoval and Zoya Alteber; middle row: David Bassan and Adi Sharbi-Yunger; top row: Lior Roitman, Mareike Grees and Adam Solomon

Seek and Destroy

11.02.2015

New strategies might help the immune system outwit cancer cells

NPM1 interacts with DNA polymerase eta and regulates polymerase eta-promoted TLS. Assay of polymerase eta and NPM1 in unirradiated (l) and ultraviolet irradiated cells ((c) after one hour, (r) after 18 hours). Blue: DNA in the nucleus; green: polymerase eta–NPM1 interaction

Living with the Quick Fix

29.12.2014

Biochemistry, Cancer, Molecular and Cell Biology, Genetics

A mechanism for keeping DNA repair mistakes to a minimum might advance the development of cancer drugs

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Top Stories

Shedding Light on the Dark Hours

Credit: Coleen Murphy, Princeton University, Princeton, NJ

Cracking the Code of a Worm's Throat

“Eight Shining Examples of Excellence”

Burning Cancer’s Bridges

Press Releases

“Eight Shining Examples of Excellence”

The Weizmann Institute of Science Ranked among the World’s Top Ten Academic Institutions

A Discovery to Set Your Heart a-Knocking