Cancer

Without the c-Kit gene, colon cancer cells grow in a disorderly, aggregated manner and are invasive (A); when c-Kit expression is restored in these cells, they revert to a more normal organization (B)

The Double Life of a Cancer Gene

15.09.2013

Space & Physics, Cancer, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A cancer-causing gene can prevent the deadly spread of a tumor at a later point in malignancy

Where Lab and Clinic Meet- Dr. Ayelet Erez Work

Where Lab and Clinic Meet

02.09.2013

Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics

Dr. Ayelet Erez finds that clinical work and lab research are a powerful combination

The tips of two adult fruit fly testes, viewed under a confocal microscope, are filled with dividing germ cells (green). About one quarter of these germ cells die by an alternative death pathway called germ cell death (pink and red)

Alternate Endings

05.06.2013

Cancer, Molecular and Cell Biology

A newly discovered cell-death pathway could help fight cancer

Human cells light up with green fluorescent markers after being penetrated by a genetically engineered virus coated with the VSV envelope protein

A Viral “Crook” Cracks Many Locks

05.06.2013

Cancer, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

How does a helpful virus often used for gene therapy break into cells?

“Deregulation scores” of hundreds of brain tumor patients: Each row corresponds to a pathway (that is, a biochemical process), and each column to a sample taken from a patient. Every colored spot stands for a number – the value of the “deregulation score” of the corresponding pathway, as determined for a particular patient. Dark blue stands for the activity of the pathway in normal brain tissue, whereas dark red indicates a high level of deviation from normal behavior. The clearly distinct group of normal b

The Path to Personalized Prognosis

13.05.2013

Cancer, Personalized Medicine, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A new approach to personalized cancer therapy profiles a tumor by its biological pathways

Lung cancer. Image: Lange 123 on Wikimedia commons

Two Tests Are Better Than One

20.03.2013

Biochemistry, Cancer, Disease, Drugs & Diagnostics, Genetics

Activity levels of a second DNA repair mechanism improve prediction of lung cancer risk

(l-r) Dr. Ofer Shoshani and Prof. Dov Zipori

Safer Stem Cell Scenario

24.02.2013

Cancer, Stem Cells, Molecular and Cell Biology

Future stem cell therapies might depend on our ability to chose those that won’t turn cancerous

Two Antibodies Are Better Than One

Two Antibodies Are Better Than One

07.02.2013

Cancer, Immunology, Disease, Drugs & Diagnostics

A new approach mimicking the body’s natural defenses could help treat a therapy-resistant breast cancer

Prostaglandins guard stem cells by increasing the production of an inhibitory factor in the mesenchymal bone marrow cells. Mesenchymal cells are marked with a green protein (left); the inhibitory factor is red (center). Combined image (right): Treatment with prostaglandins (bottom) increases the secretion of the inhibitory factor

How Stem Cells Stay Young

29.11.2012

Cancer, Stem Cells, Immunology, Disease, Drugs & Diagnostics

A rare subgroup of immune cells act as stem cell “bodyguards”

Prof. Rivka Dikstein

The Coupling Protein

18.11.2012

Biochemistry, Cancer, Genetics

A newly discovered protein may present a suitably narrow target for cancer treatments

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