Disease, Drugs & Diagnostics

Kill the Messenger

Kill the Messenger

12.06.2012

Cancer, Disease, Drugs & Diagnostics

A small molecule developed at the Weizmann Institute prevents a cancer-causing message from entering the cell nucleus

The molecular structure of Spanish flu protein (hemagglutin) bound to a computationally designed protein (green). The designed protein binds the viral protein tightly and with high specificity, blocking the protein's function and neutralizing viral infectivity

Matchmaker

23.05.2012

Biochemistry, Viruses & Microorganisms, Disease, Drugs & Diagnostics, Structural Biology

A new method of redesigning protein molecules may yield novel drugs.

The two faces of BID. When duty calls, it leaves the cell nucleus to initiate cell suicide. Illustration: Elite Avni

Meeting Places

23.04.2012

Stem Cells, Molecular and Cell Biology, Disease, Drugs & Diagnostics

How does one protein direct two different life-or-death activities in the cell?

Profs. Bernardo Vidne and Talila Volk. From human hearts to fruit fly hearts

Heart and Mind

02.04.2012

Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics, Science Teaching

After a career as a top cardiac surgeon, Prof. Bernardo Vidne decided to get a Ph.D. in science

Left: Natural control mechanism blocks the enzyme's zinc active site. Right: Novel antibody works as effectively as the natural control mechanism

Immune System Tricks

19.03.2012

Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Structural Biology

A synthetic molecule causes a useful immune response in mice

Prof. Irun Cohen, DiaPep 227 developer

Phase III Clinical Trials of Diabetes Treatment

30.01.2012

Immunology, Disease, Drugs & Diagnostics, Yeda Technology Transfer, Biotechnology

Initial results show higher pancreas function after two years of treatment

Prof. Jeffrey Gerst and Rachel Kama

Unraveling Batten Disease

05.01.2012

Brain & Behavior, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

When the CLN3 gene is mutated, molecular traffic patterns are disrupted in the neurons.

Left: Natural control mechanism blocks the enzyme's zinc active site. Right: Novel antibody works as effectively as the natural control mechanism

New Antibodies Treat Autoimmune Disease in Mice

26.12.2011

Immunology, Disease, Drugs & Diagnostics, Organic Chemistry

Institute scientist “trick” the body into blocking an enzyme that abets disease processes

Electron microscope image of an effector cell inserting several appendages through endothelial cell membranes

Hide and Seek Signals

15.12.2011

Immunology, Disease, Drugs & Diagnostics

Keeping chemical signals inside the cells lining blood vessels ensures that only specially trained immune cells will find them

Andromeda Biotech: A Drug for Type 1 Diabetes Developed by Prof. Irun Cohen of the Weizmann Institute Meets Primary and Secondary Goals of Phase III Clinical Trials

Andromeda Biotech: A Drug for Type 1 Diabetes Developed by Prof. Irun Cohen of the Weizmann Institute Meets Primary and Secondary Goals of Phase III Clinical Trials

22.11.2011

Disease, Drugs & Diagnostics, Biotechnology

Pateints receiving the drug had significantly higher pancreas function than those in the control group.

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The Master Switch Turning Immune Cells into Cancer Eradicators

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Wake-Up Call for Dormant Cancer

The Master Switch Turning Immune Cells into Cancer Eradicators