Disease, Drugs & Diagnostics

The extracellular matrix as captured by a scanning electron microscope (SEM)

The Signs Are in the Matrix

12.07.2021

Life Sciences, Personalized Medicine, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Diagnostic Techniques and Drugs

Changes to the extracellular matrix could point to the future development of inflammatory bowel diseases

Avocado - a fruit abundant with beta-sitosterol. Photo credit: Shutterstock

A Natural Food Supplement May Relieve Anxiety

18.05.2021

Biochemistry, Brain & Behavior, Disease, Drugs & Diagnostics

Mice receiving the plant-derived substance were less anxious than the controls

Electron microscopy images representing different views of the MC4 receptor bound to setmelanotide, in complex with proteins activated by the binding

The Hunger Games: Uncovering the Secret of the Hunger Switch in the Brain

15.04.2021

Structural Biology, Brain & Behavior, Nutrition, Disease, Drugs & Diagnostics

A 3D structure reveals how a unique molecular switch in our brain causes us to feel full – and may help develop improved anti-obesity drugs

melanoma cells

Bacteria May Aid Anti-Cancer Immune Response

17.03.2021

Bioinformatics and Computational Biology, Cancer, Personalized Medicine, Systems Biology, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

The findings of a new study may explain the microbiome-immunotherapy connection

Evolved to Stop Bacteria, Designed for Stability

Evolved to Stop Bacteria, Designed for Stability

15.03.2021

Bioinformatics and Computational Biology, Structural Biology, Viruses & Microorganisms, Disease, Drugs & Diagnostics

New proteins, created through long-distance collaboration, might lead to the reversal of antibiotic resistance in certain bacteria

filaments melting in infected red blood cells

Killing Them Softly – With Proteasomes

08.03.2021

Biochemistry, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics

A collaborative effort reveals deadly malaria parasites’ pre-invasion strategy for softening up red blood cells

multiple myeloma drug resistant cells

Uncovering the Anti-Myeloma Resistance Files

22.02.2021

Cancer, Personalized Medicine, Immunology, Disease, Drugs & Diagnostics, Diagnostic Techniques and Drugs

From bedside to bench and back: Researchers reveal a genetic signature that could help overcome drug resistance in some of the most aggressive forms...

Colon extracellular matrix

Stress Response Protein Links Inflammatory Disease to Colon Cancer

18.02.2021

Biochemistry, Cancer, Personalized Medicine, Molecular and Cell Biology, Disease, Drugs & Diagnostics

The findings might help identify those at extra risk of this cancer and develop means of prevention

Copying Foreign Genes Helps Bacteria Withstand the Test of Time

Copying Foreign Genes Helps Bacteria Withstand the Test of Time

04.02.2021

Bioinformatics and Computational Biology, Viruses & Microorganisms, Disease, Drugs & Diagnostics, Genetics

Tracking how bacteria adopt new genes provides unique insight into their evolution, antibiotic resistance and the creation of useful bacteria in the...

Hijacking the Host Defenses Gives Bacteria an Advantage

Hijacking the Host Defenses Gives Bacteria an Advantage

25.01.2021

Systems Biology, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics

A metabolic switch in microbe-fighting macrophages signals bacteria to convert them to hotels with amenities

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Traces of Trauma in the Young Brain – and How to Erase Them

Scanning electron microscope images of the enamel layer enveloping mouse teeth

Newly Discovered Autoimmune Disorder Disrupts Tooth Enamel Development

Photo: Jonathan D. Muller

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Moonshot Provides Blueprint for Future Pandemic Drugs

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Traces of Trauma in the Young Brain – and How to Erase Them

Newly Discovered Autoimmune Disorder Disrupts Tooth Enamel Development

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