Disease, Drugs & Diagnostics

Electron microscopy images representing different views of the MC4 receptor bound to setmelanotide, in complex with proteins activated by the binding

The Hunger Games: Uncovering the Secret of the Hunger Switch in the Brain

15.04.2021

Structural Biology, Brain & Behavior, Nutrition, Disease, Drugs & Diagnostics

A 3D structure reveals how a unique molecular switch in our brain causes us to feel full – and may help develop improved anti-obesity drugs

melanoma cells

Bacteria May Aid Anti-Cancer Immune Response

17.03.2021

Bioinformatics and Computational Biology, Cancer, Personalized Medicine, Systems Biology, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

The findings of a new study may explain the microbiome-immunotherapy connection

Evolved to Stop Bacteria, Designed for Stability

Evolved to Stop Bacteria, Designed for Stability

15.03.2021

Bioinformatics and Computational Biology, Structural Biology, Viruses & Microorganisms, Disease, Drugs & Diagnostics

New proteins, created through long-distance collaboration, might lead to the reversal of antibiotic resistance in certain bacteria

filaments melting in infected red blood cells

Killing Them Softly – With Proteasomes

08.03.2021

Biochemistry, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics

A collaborative effort reveals deadly malaria parasites’ pre-invasion strategy for softening up red blood cells

multiple myeloma drug resistant cells

Uncovering the Anti-Myeloma Resistance Files

22.02.2021

Cancer, Personalized Medicine, Immunology, Disease, Drugs & Diagnostics, Diagnostic Techniques and Drugs

From bedside to bench and back: Researchers reveal a genetic signature that could help overcome drug resistance in some of the most aggressive forms...

Colon extracellular matrix

Stress Response Protein Links Inflammatory Disease to Colon Cancer

18.02.2021

Biochemistry, Cancer, Personalized Medicine, Molecular and Cell Biology, Disease, Drugs & Diagnostics

The findings might help identify those at extra risk of this cancer and develop means of prevention

Copying Foreign Genes Helps Bacteria Withstand the Test of Time

Copying Foreign Genes Helps Bacteria Withstand the Test of Time

04.02.2021

Bioinformatics and Computational Biology, Viruses & Microorganisms, Disease, Drugs & Diagnostics, Genetics

Tracking how bacteria adopt new genes provides unique insight into their evolution, antibiotic resistance and the creation of useful bacteria in the...

Hijacking the Host Defenses Gives Bacteria an Advantage

Hijacking the Host Defenses Gives Bacteria an Advantage

25.01.2021

Systems Biology, Viruses & Microorganisms, Molecular and Cell Biology, Disease, Drugs & Diagnostics

A metabolic switch in microbe-fighting macrophages signals bacteria to convert them to hotels with amenities

Helping the Brain’s Immune Cells Regain the Ground State

Helping the Brain’s Immune Cells Regain the Ground State

11.01.2021

Brain & Behavior, Systems Biology, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

An anti-inflammatory agent keeps microglia responses short and to the point

Chaperones Do the Two-Step

Chaperones Do the Two-Step

03.12.2020

Structural Biology, Brain & Behavior, Molecular and Cell Biology, Disease, Drugs & Diagnostics

Understanding how certain proteins work as a team could shed new light on the way cells defend themselves against neurodegenerative disease

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Illustration by Yael Leibovitch and Simone Dell’Ariccia

We Know What You Ate: Detailed Protein Maps Assess Intestinal Health

Dendrites that developed in a tin battery, seen under an electronic microscope. Source: Shakked Schwartz and Ayan Maity

On the Way to Building Better Batteries

Weizmann Institute of Science Moves to 100% Green Electricity

Ants vs. Humans: Putting Group Smarts to the Test

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We Know What You Ate: Detailed Protein Maps Assess Intestinal Health

Weizmann Institute of Science Moves to 100% Green Electricity

Ants vs. Humans: Putting Group Smarts to the Test