You are here

Home > Cancer genetics

Cancer genetics

Shutterstock
Why Do Cancer Patients Lose So Much Weight?
08.05.2023
Cancer, Nutrition, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics

Wasting syndrome – a deadly cancer side-effect – might be diagnosed and treated early on, according to a new study

Tissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple); cell nuclei are in blue
Immunotherapy Drugs Step on the Gas
05.03.2023
Cancer, Personalized Medicine, Molecular and Cell Biology, Immunology, Disease, Drugs & Diagnostics, Diagnostic Techniques and Drugs

Sometimes anticancer antibodies press on the gas and the brakes at the same time. New research might help them accelerate better

Collagen fibers deposited by fibroblasts in the tumor microenvironment, viewed under a microscope. The fibers form an orderly pattern in tumors with an unmutated BRCA gene (top); in contrast, in tumors of patients harboring BRCA mutations (bottom), the collagen structure is disordered
Thugs in the Cellular Neighborhood
08.02.2023
Cancer, Molecular and Cell Biology, Disease, Drugs & Diagnostics, Genetics

Weizmann Institute scientists have discovered how mutations in the BRCA genes, particularly prevalent among Ashkenazi Jews, lead to...

Patterns of epigenetic markers revealed by EPINUC on blood nucleosomes (bright-red dots)
Putting Liquid Biopsies on Solid Ground: Cancer Diagnosis from a Milliliter of Blood
08.09.2022
Cancer, Personalized Medicine, Disease, Drugs & Diagnostics, Benefiting Humanity, Biotechnology, Diagnostic Techniques and Drugs

If larger studies confirm the results of a Weizmann Institute innovation, diagnosing cancer may one day be as easy as taking blood

...
Mutations shed light on cancer
Rare Disease is a Lens on Cancer
24.11.2015
Cancer, Personalized Medicine, Systems Biology, Molecular and Cell Biology, Disease, Drugs & Diagnostics

In children, lack of a protein causes a dangerous disease. Why do cancer cells suppress the same protein?

Algorithm-generated comparisons among the genomes of cells from 450 tissue samples: The analysis revealed a striking similarity (red colors, upper right rectangle) in tRNA signatures among cancerous cells and healthy dividing cells, as well as a degree of similarity among the non-dividing cells (red colors, lower left rectangle), whereas no such similarity (blue) was found when dividing cells were compared with non-dividing ones
Cellular Signature Style
23.11.2014
Cancer, Stem Cells, Genetics

Synonyms in the gene code spell differences in cell division

Without the c-Kit gene, colon cancer cells grow in a disorderly, aggregated manner and are invasive (A); when c-Kit expression is restored in these cells, they revert to a more normal organization (B)
The Double Life of a Cancer Gene
15.09.2013
Space & Physics, Cancer, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A cancer-causing gene can prevent the deadly spread of a tumor at a later point in malignancy

“Deregulation scores” of hundreds of brain tumor patients: Each row corresponds to a pathway (that is, a biochemical process), and each column to a sample taken from a patient. Every colored spot stands for a number – the value of the “deregulation score” of the corresponding pathway, as determined for a particular patient. Dark blue stands for the activity of the pathway in normal brain tissue, whereas dark red indicates a high level of deviation from normal behavior. The clearly distinct group of normal b
The Path to Personalized Prognosis
13.05.2013
Cancer, Personalized Medicine, Molecular and Cell Biology, Genetics, Bioinformatics and Computational Biology

A new approach to personalized cancer therapy profiles a tumor by its biological pathways

Prof. Rivka Dikstein
The Coupling Protein
18.11.2012
Biochemistry, Cancer, Genetics

A newly discovered protein may present a suitably narrow target for cancer treatments

Prof. Roy Bar-Ziv and Dr. Lior Nissim. Identifying cancer
The Nano-Surgeon Always Signals Twice
07.03.2011
Cancer, Disease, Drugs & Diagnostics, Genetics

A new genetic sensor kills only the malignant cancer cells in a test tube.

Pages

Top Stories

See All >
Shutterstock

Dumpster Diving in Cancer Tissue Uncovers an Immune Evasion Mechanism

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

Peripheral sensory neurons in a laboratory dish

Unlocking a Secret Nerve Cell Regenerator

Shutterstock

Surviving on an Empty Battery

Press Releases
See All >
A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta
06.09.2023
Human Embryo Models Grown from Stem Cells
Shutterstock
17.08.2023
Surviving on an Empty Battery
14.08.2023
A “Jupiter” Hotter than the Sun
Most Popular Articles

Checking the Dosage

Prof. Yoram Groner is a pioneer in Down syndrome research

Let it Rain

Added particles in the atmosphere could be affecting rainfall patterns

The Limits of Computing

Computers can solve complex problems but they are far from omnipotent. Prof. Ran Raz of the Weizmann Institute's Computer Science and Applied Mathematics Department is trying to portray the limits...