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Protein design

Shutterstock
25.01.2024

A new algorithm may greatly speed up the process of engineering therapeutic antibodies

An illustration showing four modular enzyme fragments (highlighted) that Weizmann Institute’s CADENZ method can combine to generate active enzymes at a hitherto unseen rate
12.01.2023

In a major step toward greener industry, Weizmann Institute scientists create a computational method for generating enzymes with unprecedented...

Dr. Shiran Barber-Zucker and Prof. Sarel Fleishman. Protein Goldmine
13.04.2022

Forget crystals. AI gives Weizmann’s algorithms the means to design biomolecules with a huge range of valuable functions

Evolved to Stop Bacteria, Designed for Stability
15.03.2021

New proteins, created through long-distance collaboration, might lead to the reversal of antibiotic resistance in certain bacteria 

Fleishman and group
01.11.2018

A computational method for designing dramatically more efficient versions of enzymes may lead to new avenues of drug design and new treatments...

Designed and experimental antibody
26.09.2017

Including “non-ideal” components in the designs may be key to functional artificial proteins  

filaments
23.08.2017

Self-assembling protein complexes based on a single mutation could provide scaffolding for nanostructures

protein repair shop
01.08.2016

A “one-stop,” computer-design “shop” for stabilizing problematic proteins