Stem Cells

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Sperm Welcome – But Their Mitochondria Must Go

15.07.2024

Stem Cells, Molecular and Cell Biology, Evolution and Development, Fertility

Why do we inherit only maternal mitochondria? A new study shows how the paternal versions are deliberately destroyed

Researchers used color-coded proteins to reveal the identity of the cells in the organoids they produced. In four organoids that simulate the embryo’s central nervous system, the magenta marks proteins associated with the development of the forebrain and the midbrain, the green, the hindbrain and the red, the center of the spinal cord

From Tip to Tail

01.06.2024

Brain & Behavior, Stem Cells, Evolution and Development, Genetics

Researchers from the University of Michigan and the Weizmann Institute develop the first-ever complete central nervous system on a chip; it...

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Bacteria against Mutants

28.05.2024

Stem Cells, Systems Biology, Viruses & Microorganisms, Evolution and Development

A bacterial model helps reveal how our bodies prevent population explosions – and cancer

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Down the Rabbit Hole

08.02.2024

Math & Computer Science, Bioinformatics and Computational Biology, Stem Cells, Evolution and Development, Genetics

An innovative Weizmann Institute system for tracking the earliest stages of embryonic development, applied for the first time in rabbits, could...

A stem cell–derived human embryo model at a developmental stage equivalent to that of a human embryo at day 12 has all the compartments typical of this stage. The top sphere contains the part that will become the embryo itself, capped by the amnion; the bottom sphere is the yolk sac; the interface between them is a critical structural feature of human embryonic development. The two spheres are encapsulated by a cellular layer that will become the placenta

Human Embryo Models Grown from Stem Cells

06.09.2023

Stem Cells, Molecular and Cell Biology, Evolution and Development, Fertility, Genetics

The complete, day 14 synthetic models may open new avenues of research into infertility, drug testing and growth of tissues for transplant – as well...

Decades-Old Mystery of Red Blood Cell Production Finally Solved

Decades-Old Mystery of Red Blood Cell Production Finally Solved

27.04.2023

Stem Cells, Molecular and Cell Biology, Disease, Drugs & Diagnostics

Identifying the cells producing the hormone EPO may lead to the development of new therapies for treating anemia resulting from kidney disease and...

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Treating a Heart Attack before It Happens

08.03.2023

Stem Cells, Molecular and Cell Biology, Disease, Drugs & Diagnostics

A preventive procedure, performed on healthy mice, improved their recovery from later-occurring cardiac injury, reshaping our knowledge of...

Development of synthetic mouse embryo models inside beakers

Without Egg, Sperm or Womb: Synthetic Mouse Embryo Models Created Solely from Stem Cells

01.08.2022

Stem Cells, Molecular and Cell Biology, Evolution and Development, Genetics, Technology & Applications

The method opens new vistas for studying how stem cells self-organize into organs and may in the future help produce transplantable tissues

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Creating the Cells That Can Be Everything and More

12.07.2022

Stem Cells, Molecular and Cell Biology, Immunology, Evolution and Development, Genetics

Removing a newly discovered “lock” from DNA’s packaging can restore limitless abilities to early cells

Settled at Birth: Blood Vessels Remember Their Origins

Settled at Birth: Blood Vessels Remember Their Origins

25.05.2022

Stem Cells, Systems Biology, Molecular and Cell Biology, Evolution and Development

Blood vessels originating from lymphatic vessels were found to be tailored to specific functions

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Ants vs. Humans: Putting Group Smarts to the Test

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