Stem Cells

Developing bone in normal (top) and mutant (bottom) embryos. Protrusions in a developing bone are formed by a distinct class of cells (green) that differ from the regular bone-forming cells (yellow-orange). Incorrect regulation and distribution of these cells leads to irregularities in the shape of the forming bone

The Collagen Paradox

12.02.2014

Stem Cells, Molecular and Cell Biology, Genetics

How does an oxygen-demanding biological process cope with low-oxygen conditions?

New Stem Cells Go Back Further

New Stem Cells Go Back Further

31.10.2013

Stem Cells, Molecular and Cell Biology, Genetics

Scientists isolate new human pluripotent stem cells capable of generating “humanized” mouse models containing human-derived tissues

Left column: Previous method for creating induced pluripotent stem cells (iPSCs); right column: iPSCs produced with the new method developed by Dr. Hanna. Top: Skin cells (red); center: iPSCs from skin cells (green); bottom: superimposed top and center images. Skin cells that have been reprogrammed into iPSCs appear light yellow. Only a small percentage of the cells on the left have been reprogrammed, in contrast with the high success rate seen with the new method on the right

Stem Cell Reprogramming Made Easier

17.09.2013

Stem Cells, Molecular and Cell Biology, Genetics

Weizmann Institute scientists show that removing one protein from adult cells enables them to efficiently turn back the clock to a stem-cell-like...

(l-r) Dr. Ofer Shoshani and Prof. Dov Zipori

Safer Stem Cell Scenario

24.02.2013

Cancer, Stem Cells, Molecular and Cell Biology

Future stem cell therapies might depend on our ability to chose those that won’t turn cancerous

Prostaglandins guard stem cells by increasing the production of an inhibitory factor in the mesenchymal bone marrow cells. Mesenchymal cells are marked with a green protein (left); the inhibitory factor is red (center). Combined image (right): Treatment with prostaglandins (bottom) increases the secretion of the inhibitory factor

How Stem Cells Stay Young

29.11.2012

Cancer, Stem Cells, Immunology, Disease, Drugs & Diagnostics

A rare subgroup of immune cells act as stem cell “bodyguards”

Stem cells (alkaline phosphatase staining) from the lab of Dr. Jacob Hanna

Switches for Stem Cells

20.08.2012

Space & Physics, Cancer, Stem Cells, Molecular and Cell Biology, Genetics

When a critical step in stem cell differentiation goes awry, it can lead to cancer

Judging DNA by Its Cover

Judging DNA by Its Cover

23.07.2012

Cancer, Stem Cells, Molecular and Cell Biology, Genetics

A newly-discovered molecular mechanism might explain the link between stem cells and cancer

Top: Dr. Noa Chapal-Ilani and Yitzhak Reizel. Bottom: Drs. Rivka Adar and Shalev Itzkovitz, and Profs. Nava Dekel and Ehud Shapiro

Skeletons (and other Organs) in the Cell Family Tree

15.05.2012

Cancer, Stem Cells, Math & Computer Science, Bioinformatics and Computational Biology

Tracing the lineages of cells resolves some outstanding questions in biology

The two faces of BID. When duty calls, it leaves the cell nucleus to initiate cell suicide. Illustration: Elite Avni

Meeting Places

23.04.2012

Stem Cells, Molecular and Cell Biology, Disease, Drugs & Diagnostics

How does one protein direct two different life-or-death activities in the cell?

Mouse cell lineage tree. Oocytes are in red, bone marrow stem cells in yellow, demonstrating that the two form separate clusters with only a distant relationship

Lineage Trees Reveal Cells’ Histories

23.02.2012

Biochemistry, Stem Cells, Bioinformatics and Computational Biology

A new method is helping to resolve controversies and answer some open questions in biology.

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Shedding Light on the Dark Hours

Credit: Coleen Murphy, Princeton University, Princeton, NJ

Cracking the Code of a Worm's Throat

“Eight Shining Examples of Excellence”

Burning Cancer’s Bridges

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“Eight Shining Examples of Excellence”

The Weizmann Institute of Science Ranked among the World’s Top Ten Academic Institutions

A Discovery to Set Your Heart a-Knocking