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Dan Tawfik

Fleishman and group

A computational method for designing dramatically more efficient versions of enzymes may lead to new avenues of drug design and new treatments...

Evolution of a protein


A protein "time machine" reveals how proteins may have evolved 

protein repair shop

A “one-stop,” computer-design “shop” for stabilizing problematic proteins

Prof. Dan Tawfik

Prof. Dan Tawfik is the recipient of the Teva Award for Excellence in Memory of Eli Hurvitz

 Prof. Dan Tawfik, Dr. Mikael Elias, Korina Goldin and Alon Wellner

How do bacteria cope with toxins that resemble nutrients?

Rejecting Arsenate

Institute scientists reveal how bacteria living in toxic environments identify and expel the poison


Engineered Enzyme Protects against Nerve Gas

“Natural selection” in a test tube improves the enzyme efficiency by a factor of thousands

Weizmann Institute Scientists used Accelerated Evolution to Develop: Enzymes that Provide Protection Against Nerve Gas
Protection against nerve gas attack is a significant component of the defense system of many countries around the world....
Three-dimensional structure of an enzyme, serum paraoxonase (PON1), which has been mutated in the lab of Prof. Dan Tawfik through directed evolution to endow the enzyme with new functions

From solving the structure of crystallized proteins to creating computer simulations of protein dynamics, Institute scientists...