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Biological Regulation

Natural anticancer antibodies (green) bound to a single ovarian tumor cell; the cell’s nucleus is in blue. Viewed with confocal microscopy

Natural antibodies found in tumors could point the way toward improved immunotherapy 

(l-r) Dr. Ashish Noronha, Prof. Yosef Yarden, and Dr. Nishanth Belugali Nataraj

A gene for transport helps aggressive cancer cells move and spread 

Fluorescence microscopy image of Salmonella (green) engulfed by splenic macrophages (red; blue – cell nuclei)

An intriguing subset of immune cells enables bacteria to flourish

Lymphatic vessels (green) and bones (red) in a one-month-old zebrafish

A study of the genetic basis of blood vessel growth finds a surprise player helping cells ace this complex feat

(l-r) Prof. Amos Tanay, Dr. Yoav Mayshar, Dr. Markus Mittnenzweig and Dr. Yonatan Stelzer. Orchestrated ensembles

Reconstructing the intricate process of embryonic development one cellular frame at a time

The extracellular matrix as captured by a scanning electron microscope (SEM)

Changes to the extracellular matrix could point to the future development of inflammatory bowel diseases

When the Beads Line Up

Conserved elements reveal vital spots in the noncoding, regulatory, portions of the genome 

Hijacking the Host Defenses Gives Bacteria an Advantage

A metabolic switch in microbe-fighting macrophages signals bacteria to convert them to hotels with amenities 

cells that remember their identity

Cancer cells turn out to have memories. But these are unreliable and can end up causing trouble

immune cells in cancer

A possible cause for cancer resistance to immunotherapy could be reversed