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Molecular Genetics

Embryonic stem cells (marked in green fluorescent protein) that should become sex cells, in which the gene encoding Utx is not present. Each column shows a gene needed for sex cell development (top row – marked in red, purple and orange). After 12 days (bottom row) the expression of the four genes has stopped and, rather than develop into sperm or ova, the stem cells die
28.08.2012

Weizmann scientists discover an enzyme that is crucial for turning back the development clock in cells

Stem cells (alkaline phosphatase staining) from the lab of Dr. Jacob Hanna
20.08.2012

When a critical step in stem cell differentiation goes awry, it can lead to cancer

Hornstein_microprocessor
24.07.2012

A complex for activating certain RNAs must avoid cutting up the wrong strands

(l-r) Dr. Gili Ben-Nissan, Prof. Yosef Shaul, Dr. Michal Sharon and Oren Moscovitz
24.07.2012

How does the cell keep certain vital proteins from getting recycled?

Judging DNA by Its Cover
23.07.2012

A newly-discovered molecular mechanism might explain the link between stem cells and cancer
 

Electron micrograph of bacteriophages Image: Dr Graham Beards, Wikimedia Commons
17.07.2012

The beneficial bacteria in our guts are open to attack from viruses

Cell Reports cover: Illustration by Dr. Rita Gelin-Licht showing yeast cells mating through extensions
16.07.2012

When yeast cells want to mate, they grow extensions in the direction of  potential partners

Living Microprocessor Tunes in to Feedback
12.06.2012

What keeps the machinery for chopping functional pieces out of certain long RNA strands from cutting up the wrong kinds of RNA?
 

Budding wing from irradiated fruit fly larvae, magnified about 80 times; various aspects of apoptosis in a regular fly (left column) are compared with the mutant fly lacking the drice gene (right column). Upper row: “reporter” proteins are highlighted with green fluorescent protein; middle row: the cutting up of these reporter proteins by caspases; bottom row: numerous cells die by apoptosis in the regular fruit fly (left), whereas almost no apoptosis occurs in the fly lacking the Drice caspase (right)
11.06.2012

What separates the cells that are prone to suicide from those that are long lived?

socks
11.06.2012

Proteins must match up correctly to catch a ride from one site to another in the cell

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