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Molecular Genetics

fruit fly larval salivary gland
How Cells Spit It Out
01.01.2016
Biochemistry, Molecular and Cell Biology, Genetics, Structural Biology

How do the cells that secrete saliva or tears handle the load? 

Bones of mice at different ages, imaged with three-dimensional computer tomography. A core element at the center of the bone (highlighted in different colors) enabled the scientists to align different bones for comparison
Bones Don’t Get the Drift
19.12.2015
Evolution and Development

How do bones retain their proportions as they grow? 

Starving yeast cells
Starvation Blues
06.10.2015

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SuperPaths: A map of human biological pathways. Each node represents a biological pathway and every line shows a connection between pathways. Every connected set is a SuperPath containing several related pathways.
Stay Connected
27.05.2015
Genetics, Bioinformatics and Computational Biology

SuperPaths provide a global online resource of genetic interactions

Muscle fibers of a fruit fly larva viewed under a confocal microscope: A normal fiber has normally-shaped, properly distributed nuclei (A), whereas the nuclei of fibers with mutated MSP-300 or its interacting proteins Klar and Klaroid are distorted and distributed abnormally (B, C and D)
Use It or Lose It
11.02.2015
Molecular and Cell Biology, Genetics

Why do muscles lose their strength without exercise?

Stem cell colony with cells in the process of differentiation; from the lab of Dr. Jacob Hanna
Stopping the Stem Cell State
02.02.2015
Molecular and Cell Biology, Genetics

Before anything else, a stem cell must first put the brakes on its “stem-cell” program

Mouse islet of Langerhans; insulin-containing vesicles within beta cells are shown in white
Cells with an Edge
02.02.2015
Molecular and Cell Biology

Cells in the pancreas take on unusual shapes in order to carry out their vital work

 

Use It or Lose It
Use It or Lose It
25.12.2014
Molecular and Cell Biology

Why do muscles lose their strength without exercise?

Clusters of human embryonic stem cells that were differentiated to an early germ cell (PGC) state (colored cells). Each color reveals the expression of a different gene. (l-r) NANOS3, NANOG, OCT4 and, on the right, all three combined in a single image
Human Primordial Cells Created in the Lab
24.12.2014
Stem Cells, Molecular and Cell Biology, Fertility, Genetics

A cell programming technique developed at the Weizmann Institute turns them into the earliest...

Algorithm-generated comparisons among the genomes of cells from 450 tissue samples: The analysis revealed a striking similarity (red colors, upper right rectangle) in tRNA signatures among cancerous cells and healthy dividing cells, as well as a degree of similarity among the non-dividing cells (red colors, lower left rectangle), whereas no such similarity (blue) was found when dividing cells were compared with non-dividing ones
Cellular Signature Style
23.11.2014
Cancer, Stem Cells, Genetics

Synonyms in the gene code spell differences in cell division

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An electron microscope view of phages duplicated inside bacterial cells that possess the immune system discovered in the new study. This immune system attaches a ubiquitin-like protein (marked by black dots and white arrows) to the tails of these phages, preventing them from infecting other bacterial cells

Catch a Virus by Its Tail

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Sperm Welcome – But Their Mitochondria Must Go

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Sticking a Pin in Cancer

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A Sweet New MRI Method “Lights Up” Pancreatic Cancer

Press Releases
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19.05.2024
Excellence, Resilience and Diligence: Meet the Weizmann Institute of Science’s Honorary PhD Recipients
A charred basket pattern on a jar from the time of the 586 BCE Babylonian destruction of Jerusalem (Photo: Johanna Regev)
30.04.2024
Beating the Plateau
15.04.2024
Shaping the Role of Future Physician-Scientists
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One Protein, Two Programs

A cell’s decision to commit suicide involves an exchange of information between two suicide mechanisms

Checking the Dosage

Prof. Yoram Groner is a pioneer in Down syndrome research

The Limits of Computing

Computers can solve complex problems but they are far from omnipotent. Prof. Ran Raz of the Weizmann Institute's Computer Science and Applied Mathematics Department is trying to portray the limits...