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Molecular Genetics

Bones of mice at different ages, imaged with three-dimensional computer tomography. A core element at the center of the bone (highlighted in different colors) enabled the scientists to align different bones for comparison
19.12.2015

How do bones retain their proportions as they grow? 

Starving yeast cells
06.10.2015

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SuperPaths: A map of human biological pathways. Each node represents a biological pathway and every line shows a connection between pathways. Every connected set is a SuperPath containing several related pathways.
27.05.2015

SuperPaths provide a global online resource of genetic interactions

Muscle fibers of a fruit fly larva viewed under a confocal microscope: A normal fiber has normally-shaped, properly distributed nuclei (A), whereas the nuclei of fibers with mutated MSP-300 or its interacting proteins Klar and Klaroid are distorted and distributed abnormally (B, C and D)
11.02.2015

Why do muscles lose their strength without exercise?

Stem cell colony with cells in the process of differentiation; from the lab of Dr. Jacob Hanna
02.02.2015

Before anything else, a stem cell must first put the brakes on its “stem-cell” program

Mouse islet of Langerhans; insulin-containing vesicles within beta cells are shown in white
02.02.2015

Cells in the pancreas take on unusual shapes in order to carry out their vital work

 

Use It or Lose It
25.12.2014

Why do muscles lose their strength without exercise?

Clusters of human embryonic stem cells that were differentiated to an early germ cell (PGC) state (colored cells). Each color reveals the expression of a different gene. (l-r) NANOS3, NANOG, OCT4 and, on the right, all three combined in a single image
24.12.2014

A cell programming technique developed at the Weizmann Institute turns them into the earliest...

Algorithm-generated comparisons among the genomes of cells from 450 tissue samples: The analysis revealed a striking similarity (red colors, upper right rectangle) in tRNA signatures among cancerous cells and healthy dividing cells, as well as a degree of similarity among the non-dividing cells (red colors, lower left rectangle), whereas no such similarity (blue) was found when dividing cells were compared with non-dividing ones
23.11.2014

Synonyms in the gene code spell differences in cell division

Fluorescent image of Baker's yeast cells showing that the yeast Presenilin-like protein, Ypf1 (green), is found in the same cellular area as Presenilin, around the nucleus
18.11.2014

Weizmann Institute researchers reveal an unusual cellular mechanism that may be faulty in Alzheimer’s disease

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