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Molecular Genetics

(l-r) Drs. Yael Elbaz-Alon and Maya Schuldiner
03.08.2014

A cellular organelle reveals a surprising backup resource for obtaining important building materials

Genes that affect only half the population will have double the mutation rate
28.07.2014

Weizmann Institute researchers explain why genetic fertility problems can persist in a population

 

Wild type megakaryocyte
21.07.2014

Tiny bits of RNA are found to play a crucial role in blood cell maturation

(l-r) Drs. Maya Schuldiner and Jacob Hanna
15.06.2014
Two young scientists from the Weizmann Institute of Science, Drs. Maya Schuldiner and Jacob Hanna, are among 40 world-leading...
Where Have all the Mitochondria Gone?
15.05.2014

Weizmann Institute researchers shed light on a crucial step in fertilization
 

Yeast tRNA. Blue and gray are the anticodon end, purple translates to amino acid. Image: Yikrazuul via Wikimedia Commons
03.04.2014

Translators in the cell help out when a teammate is in trouble

Developing bone in normal (top) and mutant (bottom) embryos. Protrusions in a developing bone are formed by a distinct class of cells (green) that differ from the regular bone-forming cells (yellow-orange). Incorrect regulation and distribution of these cells leads to irregularities in the shape of the forming bone
12.02.2014

How does an oxygen-demanding biological process cope with low-oxygen conditions?

New Stem Cells Go Back Further
31.10.2013

Scientists isolate new human pluripotent stem cells capable of generating “humanized” mouse models containing human-derived tissues
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Pre-leukemic stem cells (top) with both mutated and healthy copies of the RUNX1 gene already display some of the characteristics of acute myeloid leukemia (AML). When the non-mutated copy of the gene is inactivated, disruptions in the spindle-assembly-checkpoint phase of cell division trigger cell death
29.09.2013

Weizmann Institute researchers discover that a “standoff” between a mutated gene and its normal counterpart keeps certain cancer cells alive...

Left column: Previous method for creating induced pluripotent stem cells (iPSCs); right column: iPSCs produced with the new method developed by Dr. Hanna. Top: Skin cells (red); center: iPSCs from skin cells (green); bottom: superimposed top and center images. Skin cells that have been reprogrammed into iPSCs appear light yellow. Only a small percentage of the cells on the left have been reprogrammed, in contrast with the high success rate seen with the new method on the right
17.09.2013

Weizmann Institute scientists show that removing one protein from adult cells enables them to efficiently turn back the clock to a stem-cell-like...

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