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Molecular Genetics

(l-r) Drs. Yael Elbaz-Alon and Maya Schuldiner
Contacts
03.08.2014
Biochemistry, Molecular and Cell Biology

A cellular organelle reveals a surprising backup resource for obtaining important building materials

Genes that affect only half the population will have double the mutation rate
Mutations from Venus, Mutations from Mars
28.07.2014
Molecular and Cell Biology, Genetics

Weizmann Institute researchers explain why genetic fertility problems can persist in a population

 

Wild type megakaryocyte
Master Key
21.07.2014
Molecular and Cell Biology, Immunology, Genetics

Tiny bits of RNA are found to play a crucial role in blood cell maturation

(l-r) Drs. Maya Schuldiner and Jacob Hanna
Two scientists from the Weizmann Institute of Science are among a list of 40 world-leading young scientists chosen by the journal Cell
15.06.2014
Stem Cells, Molecular and Cell Biology, Genetics
Two young scientists from the Weizmann Institute of Science, Drs. Maya Schuldiner and Jacob Hanna, are among 40 world-leading...
Where Have all the Mitochondria Gone?
Where Have all the Mitochondria Gone?
15.05.2014
Molecular and Cell Biology, Fertility, Genetics

Weizmann Institute researchers shed light on a crucial step in fertilization
 

Yeast tRNA. Blue and gray are the anticodon end, purple translates to amino acid. Image: Yikrazuul via Wikimedia Commons
Backup
03.04.2014
Molecular and Cell Biology, Genetics

Translators in the cell help out when a teammate is in trouble

Developing bone in normal (top) and mutant (bottom) embryos. Protrusions in a developing bone are formed by a distinct class of cells (green) that differ from the regular bone-forming cells (yellow-orange). Incorrect regulation and distribution of these cells leads to irregularities in the shape of the forming bone
The Collagen Paradox
12.02.2014
Stem Cells, Molecular and Cell Biology, Genetics

How does an oxygen-demanding biological process cope with low-oxygen conditions?

New Stem Cells Go Back Further
New Stem Cells Go Back Further
31.10.2013
Stem Cells, Molecular and Cell Biology, Genetics

Scientists isolate new human pluripotent stem cells capable of generating “humanized” mouse models containing human-derived tissues
 ...

Pre-leukemic stem cells (top) with both mutated and healthy copies of the RUNX1 gene already display some of the characteristics of acute myeloid leukemia (AML). When the non-mutated copy of the gene is inactivated, disruptions in the spindle-assembly-checkpoint phase of cell division trigger cell death
Leukemia Cells are Addicted to a Healthy Gene
29.09.2013
Cancer, Personalized Medicine, Molecular and Cell Biology, Genetics

Weizmann Institute researchers discover that a “standoff” between a mutated gene and its normal counterpart keeps certain cancer cells alive...

Left column: Previous method for creating induced pluripotent stem cells (iPSCs); right column: iPSCs produced with the new method developed by Dr. Hanna. Top: Skin cells (red); center: iPSCs from skin cells (green); bottom: superimposed top and center images. Skin cells that have been reprogrammed into iPSCs appear light yellow. Only a small percentage of the cells on the left have been reprogrammed, in contrast with the high success rate seen with the new method on the right
Stem Cell Reprogramming Made Easier
17.09.2013
Stem Cells, Molecular and Cell Biology, Genetics

Weizmann Institute scientists show that removing one protein from adult cells enables them to efficiently turn back the clock to a stem-cell-like...

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Scanning electron microscope images of the enamel layer enveloping mouse teeth
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