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Biological Chemistry

Locally Produced Proteins

How do long nerve extensions get a crucial molecule to an injury site in time?

(l-r) Dr. Gili Ben-Nissan, Prof. Yosef Shaul, Dr. Michal Sharon and Oren Moscovitz

How does the cell keep certain vital proteins from getting recycled?

The future of fuel? Image: Thinkstock

The sequence will help researchers design better means of recycling waste and producing biofuel

Prof. Ehud Shapiro, Dr. Rivka Adar, Adam Spiro and Noa Chapal-Ilani

Do chemotherapy drugs miss a hidden reservoir of cancer cells?

Dr. Ida Rishal and Prof. Michael Fainzilber. Ping-Pong signals

“Ping-Pong” signals in large cells help them assess their own length

   Leukemia cells. Image: Wikimedia commons, NIH

Research led by Weizmann Institute scientists shows why leukemia often returns

(l-r) Ido Kaminsky, Prof. Eitan Reuveny, Ruth Meller, Raz Palty and Dr. Adi Raveh. Steady supply

What keeps a cellular “warehouse” from overfilling?

The molecular structure of Spanish flu protein (hemagglutin) bound to a computationally designed protein (green). The designed protein binds the viral protein tightly and with high specificity, blocking the protein's function and neutralizing viral infectivity

 A new method of redesigning protein molecules may yield novel drugs.

Top: Dr. Noa Chapal-Ilani and Yitzhak Reizel. Bottom: Drs. Rivka Adar and Shalev Itzkovitz, and Profs. Nava Dekel and Ehud Shapiro

Tracing the lineages of cells resolves some outstanding questions in biology

 Israel Structural Proteomics Center (ISPC) illustration

Israel’s leadership in structural biology leads to the establishment of an Instruct Core Centre